The ECETOC-Targeted Risk Assessment Tool for Worker Exposure Estimation in REACH Registration Dossiers of Chemical Substances-Current Developments

International Journal of Environmental Research and Public Health
Jan UrbanusMatthias Wormuth

Abstract

(1) Background: The ECETOC Targeted Risk Assessment (TRA) tool is widely used for estimation of worker exposure levels in the development of dossiers for REACH registration of manufactured or imported chemical substances in Europe. A number of studies have been published since 2010 in which the exposure estimates of the tool are compared with workplace exposure measurement results and in some instances an underestimation of exposure was reported. The quality and results of these studies are being reviewed by ECETOC. (2) Methods: Original exposure measurement data from published comparison studies for which six or more data points were available for each workplace scenario and a TRA estimate had been developed to create a curated database to examine under what conditions and for which applications the tool is valid or may need adaptation. (3) Results: The published studies have been reviewed for completeness and clarity and TRA estimates have been constructed based on the available information, following a set of rules. The full review findings are expected to be available in the course of 2021. (4) Conclusions: The ECETOC TRA tool developers periodically review the validity and limitations of their tool, in line with internatio...Continue Reading

References

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Jul 20, 2012·Environmental Toxicology and Pharmacology·Małgorzata Kupczewska-DobeckaSławomir Brzeźnicki
Mar 19, 2014·Environmental Science. Processes & Impacts·Chris MoneyJan Urbanus
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Software Mentioned

ECEL
ECETOC TRA
CHESAR
Advanced REACH Tool
TRA
ECETOC
EASE
REACH
ETEAM

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