The ecotoxicology of hormonally active micropollutants

Water Science and Technology : a Journal of the International Association on Water Pollution Research
John P Sumpter

Abstract

There has been intense research and wide public interest in hormonally active micropollutants present in the aquatic environment for more than a decade. This group of micropollutants contains a large number of structurally diverse chemicals with quite different origins. Some are natural hormones, others pharmaceuticals, both veterinary and human, and yet others are chemicals which are hormonally active by accident, not design. Most of these hormonally active micropollutants enter the aquatic environment in effluent from (STWs). Hence, the highest concentrations of these chemicals will be in rivers heavily impacted by effluent, especially effluent from poorly performing STWs. In some cases river concentrations of a hormonally active micropollutant are well established, but in many cases they are not. It is important to know "real world" concentrations, so that laboratory ecotoxicological studies can be conducted at environmentally relevant concentrations.Fish, as vertebrates, have endocrine systems very similar to those of mammals. This means that if a micropollutant is hormonally active in a mammal, it is very likely to also be active and cause similar or related effects, in fish. It is currently less clear whether or not these...Continue Reading

Citations

May 22, 2009·Annals of the New York Academy of Sciences·Werner KloasIlka Lutz
Sep 8, 2010·Environmental Toxicology and Chemistry·Britta GrillitschErich Möstl
Jan 21, 2010·Environmental Pollution·Heidemarie SchaarNorbert Kreuzinger
Jul 1, 2016·Nature Protocols·Helen L BridleAndrea I Schäfer

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