The effect of a postoperative course of oral prednisone on postoperative morbidity following childhood tonsillectomy

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Emily MacasseyAndrew Gray

Abstract

Tonsillectomy is a common procedure with a wide range of described operative techniques and usage of perioperative medications. Single-dose intraoperative dexamethasone has been shown to decrease postoperative nausea and pain and improve return to normal diet. The aim was to determine if a course of oral postoperative steroids would further decrease postoperative morbidity following tonsillectomy in children. Randomized, placebo-controlled, double-blinded trial. Power analysis recommended 198 participants. A university hospital and private hospital. The authors compared a 5-day course of oral prednisolone with placebo in a pediatric population (3-16 years) undergoing tonsillectomy to assess effects on postoperative pain, nausea, and vomiting and return to normal function. They also assessed the effect of corticosteroids on sleep duration and aspects of sleep quality. The results showed no significant difference between the 2 groups when analyzed for differences in the above variables both overall and at each of the postoperative 10 time points (pain, P = .478; nausea and vomiting, P = .556; return to normal diet well, P = .234; return to normal activity, P = .668; bedtime, P = .056; number of times awake during the night, P = ....Continue Reading

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References

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Citations

Oct 8, 2014·The Laryngoscope·Soo K ParkDong W Lee
Aug 12, 2014·European Annals of Otorhinolaryngology, Head and Neck Diseases·I ConstantUNKNOWN SFORL Work Group
May 26, 2015·Anaesthesia Critical Care & Pain Medicine·Christophe AvelineFrancis Bonnet
Jan 18, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·David O FrancisSivakumar Chinnadurai
Jul 26, 2017·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·James G SandersPatrick J D Dawes
Oct 14, 2017·Current Opinion in Otolaryngology & Head and Neck Surgery·Patrick CarpenterJeremy D Meier
Nov 19, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Chernkwan TitirungruangP Hirunwiwatkul
Jul 28, 2020·Clinical Pediatrics·Bryce Randall NoblittKenneth C Iverson
Nov 25, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ariana G GreenwellKevin D Pereira
Mar 19, 2021·Ear, Nose, & Throat Journal·Michael E KubalaGresham T Richter
Jul 7, 2021·International Journal of Pediatric Otorhinolaryngology·Carolina B de AzevedoEdwin Tamashiro

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