PMID: 7236577May 1, 1981Paper

The effect of acute dietary restriction on muscle fibre number in weanling rats

The British Journal of Nutrition
D K LaymanP V Hegarty


1. Male Sprague-Dawley rats were allocated at 100 g into either an ad lib.-fed control group or a food-restricted group. The restricted group was fed for 9 d at 25% of ad lib. intake. Controls were killed at a body-weight of 100 g and 29 d of age. 2. The effects of food restriction on muscle weight, fibre number, fibre diameter, DNA, and protein were examined in three skeletal muscles, the soleus, plantaris and extensor digitorum longus (EDL). 3. Acute dietary restriction caused body- and muscle-weight loss and a decrease in both the number and cross-sectional area of muscle fibres in each of the muscles. 4. The restriction halted growth-related increases in DNA in all muscles and decreased the protein:DNA value in the plantaris and EDL. 5. These results indicate that present theories describing cellular development are not adequate to define growth potential or growth retardation of skeletal muscle.


Dec 1, 1977·Journal of Neurology, Neurosurgery, and Psychiatry·M Swash, M S Schwartz
Mar 1, 1975·The British Journal of Nutrition·J W Dickerson, P A McAnulty
Nov 1, 1975·The British Journal of Nutrition·N C SticklandG Goldspink
May 2, 1970·Lancet·E M Widdowson
Feb 1, 1973·The American Journal of Physiology·L C MaxwellD A Lieberman
Jan 1, 1972·The Journal of Nutrition·R E Howarth
Mar 1, 1968·The Journal of Experimental Zoology·R W Rowe
Sep 1, 1968·The Journal of Clinical Investigation·J L Knittle, J Hirsch
Jul 1, 1966·The Journal of Nutrition·M Winick, A Noble
Mar 1, 1980·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·W J Gonyea
Sep 1, 1980·The British Journal of Nutrition·P V Hegarty, K O Kim
Mar 1, 1964·The American Journal of Anatomy·M ENESCO, D PUDDY
Jul 1, 1965·The American Journal of Physiology·G GOLDSPINK
Nov 1, 1962·Journal of Clinical Pathology·R D Montgomery

❮ Previous
Next ❯


May 1, 1984·The British Journal of Nutrition·A C Hooper
Dec 17, 2014·Journal of Animal Physiology and Animal Nutrition·J Pereyra-VenegasI Jiménez-Estrada
Jun 1, 1987·Biulleten' eksperimental'noĭ biologii i meditsiny·L M NepomniashchikhG I Nepomniashchikh
Jan 1, 1985·Basic Research in Cardiology·J ZähringerG Stäb

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.