The effect of adjuvant calcium phosphate coating on a porous-coated femoral stem

Clinical Orthopaedics and Related Research
M TanzerGeorge Wells

Abstract

A prospective, randomized, double-blind, multicenter trial was done to determine if the addition of hydroxyapatite and tricalcium phosphate to the porous coating of a cementless femoral component would result in improved clinical and radiographic outcomes. Patients were randomized to receive identical porous-coated stems with (n = 159 hips) or without (n = 159 hips) hydroxyapatite and tricalcium phosphate coating. At 2 to 5 years followup (mean, 37 months), no implants were revised for aseptic loosening. There was no difference in clinical function between the two groups with respect to the Harris hip score or Western Ontario and McMaster Universities Osteoarthritis Index scores. Bony ingrowth occurred frequently in both groups with 99% of the hydroxyapatite and tricalcium phosphate group and 98% of the control group showing radiographic evidence of osseointegration. Implants coated with hydroxyapatite and tricalcium phosphate had significantly fewer radiolucencies adjacent to the porous coating, indicative of improved osseointegration. Radiolucencies were present in Gruen Zones 1, 7, 8, or 14 in 25% of the control group and in 7% of the hydroxyapatite and tricalcium phosphate group. This improved osseointegration could serve a...Continue Reading

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Citations

Apr 22, 2015·The Open Biomedical Engineering Journal·X LinY Liu
Jan 29, 2008·Clinical Orthopaedics and Related Research·Andras HeijinkJean D Sibonga
Jan 30, 2015·Journal of Orthopaedic Surgery and Research·Yun-Lin ChenShi-Gui Yan

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