Abstract
Alcohol abuse is associated with an increased incidence of postoperative complications in surgical patients and is a significant risk factor for the development of head and neck cancer (HNCA). We sought to determine the relationship between alcohol abuse and in-hospital mortality, postoperative complications, length of stay, and costs in HNCA surgery. Retrospective cross-sectional study. Discharge data from the Nationwide Inpatient Sample for 92,312 patients aged 18 years and older who underwent an ablative procedure for a malignant oral cavity, laryngeal, hypopharyngeal, or oropharyngeal neoplasm in 2003 to 2008, were analyzed using cross-tabulations and multivariate regression modeling. Patients who abused alcohol were more likely to have advanced comorbidity, undergo major surgical procedures, and require medical care at another facility or home healthcare after discharge. The development of alcohol withdrawal symptoms (AWS) was associated with an increased incidence of acute medical complications (odds ratio [OR]: 5.6, P < .001) and surgical complications (OR: 2.3, P < .001). After controlling for all other variables, there was no significant association of alcohol abuse or AWS with in-hospital mortality; however, alcohol a...Continue Reading
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