The effect of anaesthetic agents on induction, recovery and patient preferences in adult day case surgery: a 7-day follow-up randomized controlled trial

European Journal of Anaesthesiology
J K MooreJ Kerr

Abstract

To compare induction, pre- and post-discharge recovery characteristics and patient preferences between four anaesthetic regimens in adult day-surgery. Randomized controlled trial. In all, 1158 adults assigned to: propofol induction and maintenance, propofol induction with isoflurane/N2O, or sevoflurane/N2O maintenance, or sevoflurane/N2O alone. We prospectively recorded induction and pre-discharge recovery characteristics, collected 7-day post-discharge recovery characteristics using patient diaries and patient preferences by telephone follow-up. Recruitment rate was 73%--of the 425 refusals, 226 were not willing to risk a volatile induction. During induction, excitatory movements and breath holding were more common with sevoflurane only (P < 0.01). Injection pain and hiccup were more common with propofol induction (P < 0.01). In the recovery room and the postoperative ward, both nausea and vomiting were more common with sevoflurane only (P < 0.01). This difference disappeared within 48 h. There was no difference between groups in the mental state on awakening, recovery time, time to discharge or overnight admissions; then was also no difference in pain between the four groups for each of the seven postoperative days (P < 0.01)...Continue Reading

References

Apr 1, 1994·Anesthesiology·J LermanS Yentis
Sep 3, 1999·British Journal of Anaesthesia·P S MylesR McMahon
Jan 30, 2003·European Journal of Anaesthesiology·B J PollardE W Moore

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Citations

Jun 12, 2012·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Miaomiao ZhouShihai Zhang
Feb 6, 2014·European Journal of Pharmacology·Charles C HornJohn P Williams
May 31, 2015·Journal of Cardiothoracic and Vascular Anesthesia·Timothy E Miller, Tong J Gan
Aug 15, 2009·Current Opinion in Anaesthesiology·Henrik Eikaas, Johan Raeder
Apr 24, 2012·International Wound Journal·Daniel K O'NeillHarold Brem
Aug 8, 2014·Acta Anaesthesiologica Scandinavica·M LindqvistJ G Jakobsson
Jan 17, 2013·Acta Anaesthesiologica Scandinavica·M BrattwallJ Jakobsson
Dec 17, 2009·Current Opinion in Anaesthesiology

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