PMID: 2120554May 1, 1990Paper

The effect of antibiotics and immunostimulants on rickettsial persistence in experimental typhus infection

Mikrobiologicheskiĭ zhurnal
N D Klimchuk

Abstract

A model of experimental typhus infection has shown that not only specific protection factors but also nonspecific ones are very important to remove Rickettsia prowazekii from macroorganisms. A complex application of antibiotics and drugs increasing immunobiological reactivity of the organism (prodigiosan, methyl uracil) noticeably decreases the rickettsia persistence level in the organism of experimental animals, the indices of specific and nonspecific protection being increased.

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