The effect of antiretroviral therapy on fine-needle aspiration of salivary gland masses in HIV-infected patients.

Diagnostic Cytopathology
Amanda Ama Coleman-Eghan, Pamela Michelow

Abstract

South Africa has a very high prevalence of HIV/AIDS. Salivary gland lesions are common in HIV-infected patients. The aim of this study was to determine the pathologic entities diagnosed on fine-needle aspiration (FNA) of salivary gland masses in an HIV-infected study population that now has free access to antiretroviral (ARV) therapy and how this differs from the pathologic entities before the advent of widespread ARV availability, and if the Milan system for reporting salivary gland cytopathology (MSRSGC) can be applied to HIV-infected patients. A retrospective review was performed on confirmed HIV-infected patients who underwent FNA of salivary gland masses over a two-year period. A total of 360 patients underwent FNA of salivary gland masses within the designated time frame, 58.3% (210) females and 41.7% (150) males. Patient ages ranged from 7 months to 67 years with a mean age of 36.9 years. The parotid gland was the most biopsied salivary gland at 55.3% (199). The most common diagnosis made in patients on antiviral therapy was lymphoepithelial cyst while that in patients not on antiviral therapy was infectious (including abscess and mycobacterial infection). The most frequent neoplasms were non-Hodgkin lymphoma, pleomorphi...Continue Reading

References

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Jul 19, 2012·Diagnostic Cytopathology·Pam MichelowLiron Pantanowitz
Sep 24, 2014·Pediatric Hematology and Oncology·Ali VaranMünevver Büyükpamukçu
May 18, 2016·Current HIV/AIDS Reports·Joseph Kagaayi, David Serwadda
Aug 7, 2017·The Laryngoscope·Danielle F EytanChristine G Gourin
Jan 24, 2019·Mediterranean Journal of Hematology and Infectious Diseases·Alessandro ReGiuseppe Rossi

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