Abstract
The number of diabetic patients worldwide is increasing, and complications such as stroke and cardiovascular disease are becoming a serious cause of death. Diabetes mellitus is classified into two types according to the etiopathogenic mechanism and insulin dependence. Type 1 diabetes (T1D), an insulin-dependent diabetes mellitus, is caused by damage and destruction of pancreatic β cells that produce insulin. It is a disease that is characterized by hyperglycemia and hypoinsulinemia. Aronia berry has been used as a medicinal food in Europe. Aronia contains a variety of ingredients such as polyphenols, anthocyanins, flavonoids, and tannins. Especially, anthocyanin content in aronia berry is known to be much higher than in other plants and berries. It is known for exerting antioxidant, anti-inflammation, and anti-aging effects. Therefore, this study was conducted to investigate the effects of aronia berry extract intake in multiple low-dose streptozotocin (STZ)-induced T1D and to confirm the functional properties of aronia berry. ICR mice (6-week male) were divided into four groups: control (normal control group), STZ (100 mg/kg of STZ-induced T1D group), AR 10 (STZ with oral administration of aronia 10 mg/kg), and AR 100 (STZ wit...Continue Reading
References
May 1, 1979·The American Journal of Medicine·C D Saudek, H A Eder
Jul 1, 1989·American Journal of Epidemiology·R D MorrisA A Rimm
Jan 1, 1985·Annual Review of Medicine·C R Kahn
Aug 1, 1988·Planta medica·M D IvorraA Villar
Jan 10, 1998·Biochemistry·V B O'DonnellB A Freeman
Aug 22, 2000·British Journal of Pharmacology·S H BatesC J Bailey
Sep 8, 2000·Diabetes Care·A H MokdadJ S Marks
Sep 15, 2004·Molecular and Cellular Biochemistry·I AhmedJ Singh
Dec 30, 2004·Investigative Ophthalmology & Visual Science·Kazuhiro OhgamiShigeaki Ohno
Jan 1, 2005·Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie·S Valcheva-KuzmanovaA Belcheva
Mar 17, 2006·Free Radical Biology & Medicine·Rebecca A Simmons
Apr 19, 2007·Methods and Findings in Experimental and Clinical Pharmacology·S Valcheva-KuzmanovaA Belcheva
Aug 2, 2007·Nature Reviews. Drug Discovery·Csaba SzabóRafael Radi
May 17, 2006·Journal of Agricultural and Food Chemistry·Jozef HudecJaroslav Hlusek
Apr 9, 2009·Nature Reviews. Endocrinology·Décio L EizirikFernanda Ortis
Feb 23, 2010·Journal of Medicinal Food·Adam KokotkiewiczMaria Luczkiewicz
Oct 11, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Rosa Martha Perez GutierrezAdriana Maria Neira Gonzalez
Oct 16, 2014·World Journal of Diabetes·Ravindranath Aathira, Vandana Jain
Nov 7, 2014·Clinical Pediatric Endocrinology : Case Reports and Clinical Investigations : Official Journal of the Japanese Society for Pediatric Endocrinology·Eiji Kawasaki
Jan 20, 2015·Pharmacognosy Research·Ravi Shankara Birur EshwarappaBhadrapura Lakkappa Dhananjaya
Feb 19, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Maria J MatosClaudio Olea-Azar
Sep 8, 2016·The Journal of Dairy Research·Sunita MeenaRaghvendar Singh
Citations
Apr 20, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Man-Xia LuEun-Hee Hwang
Apr 26, 2020·Nutrients·Richard J BloomerKeith R Martin
Aug 23, 2020·Nutrients·Ahsan HameedMichal Ciborowski
Dec 20, 2018·Frontiers in Pharmacology·Rozita NaseriSaeideh Momtaz
May 30, 2019·Nutrients·Su-Min LimEun Ji Kim
Aug 29, 2018·International Journal of Molecular Sciences·Hack Sun ChoiDong-Sun Lee
Sep 6, 2020·Antioxidants·Bong-Keun JangSung-Vin Yim
May 14, 2020·Antioxidants·Hyo-Jin KimHee-Sook Jun
Jun 7, 2020·Journal of Physiology and Biochemistry·Francisco LesVíctor López
Oct 9, 2019·Food & Function·Aaron CalvanoArpita Basu
Feb 3, 2021·Journal of Food Biochemistry·Na-Ra HanHyun-Ja Jeong
Mar 11, 2021·Journal of Agricultural and Food Chemistry·Yanwen KongYuehua Wang
Jan 27, 2019·Life Sciences·Min XiangJiandong Lu
Aug 3, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Akurange Sujeevi Dammadinna WickramasingheAnoja Priyadarshani Attanayake
Sep 5, 2018·Journal of Agricultural and Food Chemistry·David Bars-CortinaMaria-Jose Motilva
Nov 19, 2021·Critical Reviews in Food Science and Nutrition·Yao ChenZhiyong He