The effect of bolus and food calculator Diabetics on glucose variability in children with type 1 diabetes treated with insulin pump: the results of RCT

Pediatric Diabetes
Marlena Błazik, Ewa Pańkowska

Abstract

The calculation of prandial insulin dose is a complex process in which many factors should be considered. High glucose variability during the day, arising from difficulties which include errors made in food counting and inappropriate insulin adjustments, influence hemoglobin A1c levels. During this study, in children using insulin pumps to manage type 1 diabetes, we compared 2-h postprandial blood glucose levels (BGL) and glucose variability when calorie tables and mental calculation were used, to when Diabetics software was used. This 3-month, randomized, open-label study involved 48 children aged 1-18 yr. Patients were educated in food counting system used in the Warsaw Pump Therapy School (WPTS) where the carbohydrate unit (CU) and the fat-protein unit (FPU) are taken into account. The children were randomly allocated to an experimental group (A) who used diabetics software and a control group (B) who used caloric tables and mental calculations. We observed significant differences (p < 0.05) between the groups in 2-h postprandial BGL's and the glucose variability parameters mean(T), SD(T), % BGL in the target range 70-180 mg/dL, and high blood glucose index HBGI. We did not observe statistically significant differences in hy...Continue Reading

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References

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Oct 27, 2006·Diabetes Care·Boris P KovatchevWilliam Clarke
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Feb 11, 2010·Journal of Diabetes Science and Technology·David Rodbard
Jun 2, 2010·Journal of Diabetes Science and Technology·Ewa Pańkowska, Marlena Błazik

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Citations

Dec 20, 2012·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Ides M Colin, Isabelle Paris
Mar 5, 2016·Journal of Research in Medical Sciences : the Official Journal of Isfahan University of Medical Sciences·Mansour SiavashMasoud Ataei Khorasgani
May 31, 2014·Journal of Diabetes Science and Technology·Signe Schmidt, Kirsten Nørgaard
Jun 7, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·P E LopezC E Smart
Jun 20, 2020·Current Diabetes Reviews·Elisa CipponeriAntonio Carlo Bossi
Mar 7, 2017·Journal of Diabetes Science and Technology·Ewa PańkowskaKarolina Mazurczak
Jun 28, 2018·Nature Reviews. Endocrinology·Martin Tauschmann, Roman Hovorka
Apr 21, 2021·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·Thomas HaakMichael Krichbaum

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