The effect of calcium and vitamin D supplementation on obesity in postmenopausal women: secondary analysis for a large-scale, placebo controlled, double-blind, 4-year longitudinal clinical trial.

Nutrition & Metabolism
Jiapeng ZhouJoan Lappe

Abstract

It is undetermined whether calcium supplementation has an effect on obesity or body composition in postmenopausal women. The purpose of the study is to detect the effect of calcium supplementation on indices of obesity and body composition. This is a secondary analysis of data from a population-based, double-blind, placebo-controlled, randomized trial designed to determine the effects of calcium and vitamin D on osteoporotic fractures. The cohort included 1179 postmenopausal women who were randomly assigned into one of three groups: 1) supplemental calcium (1400 mg/d or 1500 mg/d) plus vitamin D placebo (Ca-only group); 2) supplemental calcium (1400 mg/d or 1500 mg/d) plus supplemental vitamin D3 (1100 IU/d) (Ca + D group); or, 3) two placebos (placebo group). After applying the exclusion criteria for this analysis, 870 subjects were included in this study. The primary outcomes for the present study were changes in body mass index, trunk fat, trunk lean, and percentage of trunk fat after calcium supplementation. Changes in trunk fat, trunk lean, and percentage of trunk fat were significantly different between the calcium intervention groups (Ca-only group or Ca + D group) and the placebo group during the trial (P < 0.05). The c...Continue Reading

References

Sep 1, 1979·Journal of Clinical Gastroenterology·E M Livstone
Jul 1, 1985·The Journal of Clinical Investigation·N H BellS Shaw
Oct 1, 1988·Calcified Tissue International·Y LielN H Bell
Nov 1, 1981·The American Journal of Clinical Nutrition·J E CompstonT R Pilkington
Mar 1, 1996·The Journal of Clinical Endocrinology and Metabolism·M C ChapuyP J Meunier
Oct 10, 1997·The American Journal of Clinical Nutrition·P F JacquesD Rush
Jun 15, 1999·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R P HeaneyM J Barger-Lux
Oct 21, 2000·European Journal of Clinical Nutrition·M J Toth, A Tchernof
Jan 3, 2001·The Journal of Clinical Endocrinology and Metabolism·K M DaviesS Hinders
Apr 25, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·B R Carruth, J D Skinner
Apr 23, 2002·JAMA : the Journal of the American Medical Association·Mark A PereiraDavid S Ludwig
Dec 7, 2002·Best Practice & Research. Clinical Endocrinology & Metabolism·Ian D Caterson, Timothy P Gill
Dec 20, 2002·Obesity Research·F Xavier Pi-Sunyer
Jan 7, 2003·The Journal of Nutrition·Elena KamychevaRolf Jorde
Jan 10, 2003·The Journal of Clinical Endocrinology and Metabolism·Sonia ArunabhJohn F Aloia
Jan 24, 2003·The American Journal of Clinical Nutrition·Shamik J Parikh, Jack A Yanovski
Dec 4, 2003·Journal of the American Dietetic Association·Jean D SkinnerPaula Ziegler
Jun 19, 2004·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H P BhattoaA Balogh
Jul 1, 2004·The Journal of Steroid Biochemistry and Molecular Biology·G D CarterS Sufi
Jan 27, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M B ZemelE Silva
Apr 13, 2005·Archives of Internal Medicine·Bret H GoodpasterAnne B Newman
Jun 14, 2006·The British Journal of Nutrition·Rebecca TrowmanDavid J Torgerson
Jul 4, 2006·Journal of the American Dietetic Association·Alejandro J GonzalezAlyson J Littman
Aug 24, 2006·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Edward H Livingston
Oct 13, 2006·Journal of the American College of Nutrition·Joan M LappeRobert P Heaney
Mar 6, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Christine F Skibola
May 16, 2007·Archives of Internal Medicine·Bette CaanAndrea LaCroix
Jan 31, 2008·Frontiers of Hormone Research·Ian McPhee Chapman
Oct 3, 2008·Current Opinion in Cardiology·Dexter Canoy
Jun 3, 2009·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·R McLaughlin, G Wittert
Jul 30, 2011·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Mina C MojtahediEllen M Evans

❮ Previous
Next ❯

Citations

May 17, 2012·Nutrition Research Reviews·Qingming Song, Igor N Sergeev
May 23, 2012·Nutrition & Metabolism·Alexandra JungertMonika Neuhäuser-Berthold
Apr 22, 2014·International Journal of Molecular Sciences·Flávia Galvão Cândido, Josefina Bressan
Nov 20, 2015·Molecular Nutrition & Food Research·Alice ChaplinAndreu Palou
Nov 10, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Claudia Boucher-BerryMichael Rosenbaum
Jan 22, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·P SaneeiA Esmaillzadeh
Jul 30, 2015·European Journal of Clinical Investigation·Antigoni ManousopoulouGeorge P Chrousos
Jul 29, 2011·Nutrition·Carlos Eduardo Andrade ChagasLígia Araújo Martini
Oct 17, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Yu ZhouJoan M Lappe
Jan 20, 2015·Nutrition & Diabetes·P D ChandlerG G Bennett
Dec 15, 2016·European Journal of Clinical Nutrition·M HajimohammadiT R Neyestani
Mar 10, 2017·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Harry RobberechtNina Hermans
Mar 23, 2013·Nutrients·Simon Vanlint
Nov 3, 2016·The American Journal of Clinical Nutrition·Ping LiKemin Qi
Apr 15, 2014·The Cochrane Database of Systematic Reviews·Alison AvenellDianne O'Connell
Jul 25, 2019·Current Pharmaceutical Design·Ana Valer-MartinezMaira Bes-Rastrollo
Jun 15, 2020·BMC Medical Genetics·Bence BakosIstván Takács
Jan 1, 2015·Frontiers in Endocrinology·Richard Kremer, Vicente Gilsanz
Dec 10, 2020·International Journal of Food Sciences and Nutrition·Jee Yeon HongMi Kyung Kim

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.