The effect of carbohydrate structures on the hydrogelation ability and morphology of self-assembled structures of peptide-carbohydrate conjugates in water

Organic & Biomolecular Chemistry
Tomoya TsuzukiMasato Ikeda

Abstract

We describe the construction of peptide-carbohydrate conjugates, namely glycopeptides, capable of self-assembling in water. We found that disaccharide structures (epimer or glycosidic-bond geometry) appended to the glycopeptides have a noticeable effect on the hydrogel formation ability as well as the morphology of the self-assembled structures. The soft materials consisting of self-assembled structures with carbohydrates on their surface and various types of morphologies might be useful as matrices to investigate the function of carbohydrates in biological events.

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Citations

Jan 28, 2020·Soft Matter·Sanjoy MondalArun K Nandi
Sep 11, 2020·Proceedings of the National Academy of Sciences of the United States of America·Haoyuan WangWei Xiong
Dec 17, 2020·International Journal of Molecular Sciences·Sayuri L HigashiMasato Ikeda
Aug 3, 2021·Chemical Reviews·Lu SuGuosong Chen
Oct 3, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Joedian MorrisGuijun Wang
Dec 11, 2020·The Journal of Organic Chemistry·Guijun WangPooja Sharma
Sep 19, 2020·Journal of the American Chemical Society·Changdong HeSuwei Dong

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