The effect of carbon monoxide on lipid metabolism of human coronary arteries.

Atherosclerosis
J S SarmaR J Bing

Abstract

Human coronary arteries were perfused under sterile conditions in vitro with blood containing high or low concentrations of carbon monoxide. Lipid synthesis in the arterial wall was investigated by incorporating [14C]acetate; synthesis of the following lipids was measured: cholesterol, cholesterol ester, di- and triglycerides and phospholipids. Cholesterol uptake by the arterial wall was studied by using [3H]cholesterol as a tracer. No influence of CO on lipid synthesis in the arterial wall could be demonstrated. In contrast, arteries which were exposed to CO showed a higher uptake of cholesterol as compared to their corresponding control. The concentration of CO in the perfusate did not alter the degree of cholesterol uptake. These results are in general agreement with those of others, who found that CO significantly increases the permeability of endothelial membranes.

References

Jul 1, 1970·Annals of Internal Medicine·A F Whereat
Jan 1, 1973·Archives of Environmental Health·S M AyresH Mueller
Oct 5, 1970·Annals of the New York Academy of Sciences·R F Coburn
May 1, 1972·Atherosclerosis·C F Howard
Sep 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·H H Parving
Oct 5, 1970·Annals of the New York Academy of Sciences·P AstrupJ Wanstrup
Sep 1, 1968·Journal of Atherosclerosis Research·K KjeldsenP Astrup
Jan 1, 1968·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·J Siggaard-AndersenK Mellemgaard
Jul 1, 1969·Annals of Internal Medicine·J R Goldsmith
Mar 1, 1966·Circulation Research·H A Newman, D B Zilversmit
May 1, 1967·Journal of Atherosclerosis Research·P AstrupJ Wanstrup
Jan 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·H H ParvingM Rörth

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Citations

May 1, 1978·Atherosclerosis·G Schneiderman, T K Goldstick
Nov 13, 2001·Journal of the American College of Cardiology·S ZevinN L Benowitz
Jul 25, 2000·Archives of Environmental Health·R HerbertP J Landrigan
Apr 17, 2003·Archives of Environmental Health·James E SharmanDavid I Fraser
May 1, 1981·Issues in Health Care of Women·M P Yuson
Nov 1, 1991·Environmental Health Perspectives·D G Penney, J W Howley
Apr 1, 1975·The American Journal of Cardiology·J S SarmaR J Bing
Sep 1, 1983·Progress in Cardiovascular Diseases·D GreenF A Krumlovsky
May 21, 2004·Revista española de cardiología·Dominick J AngiolilloFilippo Crea
Aug 1, 1981·Atherosclerosis·P N Hopkins, R R Williams
Mar 1, 1981·American Heart Journal·W B Kannel
Jun 1, 1983·Disease-a-month : DM·S M Grundy
Apr 17, 2018·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Mary Rezk-Hanna, Neal L Benowitz
Dec 11, 2020·Free Radical Research·Amr AliGuangdong Yang

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