PMID: 6110703Jan 1, 1981Paper

The effect of catecholamine receptor antagonists on ethanol-induced locomotor stimulation

Journal of Neural Transmission
S LiljequistJ Engel

Abstract

The effect of various catecholamine receptor antagonists, which differ in their potency to block central dopamine and noradrenaline receptors, respectively, on ethanol-induced locomotor stimulation was investigated. It was shown that small doses of both specific dopamine (pimozide, haloperidol) and noradrenaline (phenoxybenzamine, yohimbine) receptor blocking agents statistically significantly suppressed the ethanol-induced locomotor stimulation. Of special interest in this study was the observation that remarkably small doses of clozapine completely antagonized the ethanol-induced locomotor stimulation. The possibility that this effect of clozapine is mediated via its interference with the activity of central noradrenaline and/or GABA neurons is discussed.

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Citations

Jan 1, 1983·Pharmacology, Biochemistry, and Behavior·K Kiianmaa, B Tabakoff
Jan 1, 1985·Pharmacology, Biochemistry, and Behavior·M S Dar, W R Wooles
Jul 1, 1987·Pharmacology, Biochemistry, and Behavior·J C CrabbeA Kosobud
Apr 1, 1987·Pharmacology, Biochemistry, and Behavior·D J CalcagnettiD L Margules
Jun 1, 1988·Pharmacology, Biochemistry, and Behavior·M K Ticku, S K Kulkarni
Mar 1, 1994·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·S Liljequist, K Ossowska
Jun 21, 2005·Alcohol·Julie BroadbentSharon A Koonse
Jul 4, 1998·European Journal of Pharmacology·P Boksa
Oct 1, 1998·European Journal of Pharmacology·J ChiuD A Lê
Jul 1, 1997·Pharmacology, Biochemistry, and Behavior·T J PhillipsC N Lessov
Jan 27, 1998·Pharmacology, Biochemistry, and Behavior·E H Shen, T J Phillips
Aug 15, 2000·Behavioural Brain Research·B SöderpalmJ A Engel
Jul 22, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Agustin ZapataToni S Shippenberg
Dec 12, 1997·Alcoholism, Clinical and Experimental Research·B Hitzemann, R Hitzemann
Nov 5, 1998·Alcoholism, Clinical and Experimental Research·K DemarestR Hitzemann
Feb 24, 1999·Alcoholism, Clinical and Experimental Research·K DemarestR Hitzemann
Sep 2, 1999·Alcoholism, Clinical and Experimental Research·M J ThrasherF O Risinger
Nov 21, 2013·Pharmacology, Biochemistry, and Behavior·Juan Carlos LedesmaCarlos M G Aragon
Apr 6, 2006·Alcohol·Isabel Marian Hartmann QuadrosMaria Lucia Oliveira Souza-Formigoni
Apr 21, 2016·Brain Research Bulletin·Rosana Camarini, Ricardo Marcos Pautassi
Dec 28, 2010·Pharmacology, Biochemistry, and Behavior·Rosana CamariniHelena Maria Calil
Nov 2, 2019·Pharmacology, Biochemistry, and Behavior·Lisa UleniusMia Ericson

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