Abstract
Understanding how changes in body mass index (BMI) relate to changes in mammographic density is necessary to evaluate adjustment for BMI gain/loss in studies of change in density and breast cancer risk. Increase in BMI has been associated with a decrease in percent density, but the effect on change in absolute dense area or volume is unclear. We examined the association between change in BMI and change in volumetric breast density among 24,556 women in the San Francisco Mammography Registry from 2007 to 2013. Height and weight were self-reported at the time of mammography. Breast density was assessed using single x-ray absorptiometry measurements. Cross-sectional and longitudinal associations between BMI and dense volume (DV), non-dense volume (NDV), and percent dense volume (PDV) were assessed using multivariable linear regression models, adjusted for demographics, risk factors, and reproductive history. In cross-sectional analysis, BMI was positively associated with DV [β, 2.95 cm(3); 95% confidence interval (CI), 2.69-3.21] and inversely associated with PDV (β, -2.03%; 95% CI, -2.09, -1.98). In contrast, increasing BMI was longitudinally associated with a decrease in both DV (β, -1.01 cm(3); 95% CI, -1.59, -0.42) and PDV (β,...Continue Reading
References
Nov 1, 1995·Journal of the National Cancer Institute·C ByrneR Haile
May 3, 1995·Journal of the National Cancer Institute·N F BoydM J Yaffe
Apr 2, 1997·Journal of the National Cancer Institute·N F BoydD Tritchler
Feb 3, 2005·Breast Disease·N F BoydD L Tritchler
Mar 19, 2005·Technology in Cancer Research & Treatment·John A ShepherdSteve R Cummings
Nov 15, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Gerco HaarsPetra H M Peeters
Apr 15, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Gertraud MaskarinecLaurence N Kolonel
Nov 9, 2006·Menopause : the Journal of the North American Menopause Society·Janet R GuthrieHenry G Burger
Nov 23, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Norman F BoydSalomon Minkin
Dec 19, 2007·British Journal of Cancer·M JeffreysG Davey Smith
Apr 4, 2008·American Journal of Epidemiology·Linda E KelemenCeline M Vachon
May 17, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Jane DingDouglas Easton
Sep 5, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Michael KhazenUNKNOWN Collaborators in the United Kingdom Medical Research Council Magnetic Resonance Imaging in Breast Screening (MARIBS) Study
Dec 10, 2008·International Journal of Cancer. Journal International Du Cancer·Katherine W ReevesJane A Cauley
May 5, 2009·The Lancet Oncology·Norman BoydMichael Bronskill
Jun 10, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Norman BoydSalomon Minkin
Jan 26, 2010·Medical Physics·Serghei MalkovJohn A Shepherd
Feb 10, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Zoe AitkenIsabel dos Santos Silva
Jul 10, 2010·Journal of the National Cancer Institute·Norman F BoydSalomon Minkin
Oct 6, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Mariëtte LokateCarla H Van Gils
May 26, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·John A ShepherdSteven R Cummings
Sep 14, 2011·American Journal of Epidemiology·Holly R HarrisKarin B Michels
Aug 7, 2012·Breast Cancer Research and Treatment·Hilda RazzaghiRobert C Millikan
Feb 23, 2013·Journal of Oncology·Amina AmadouIsabelle Romieu
Apr 16, 2013·Critical Reviews in Eukaryotic Gene Expression·Mary C PlaydonHenry J Thompson
Jul 31, 2013·The Lancet Oncology·T J KeyP Vineis
Oct 31, 2013·American Journal of Epidemiology·Laura BagliettoGraham G Giles
Dec 11, 2013·PloS One·Jeff WangJohn A Shepherd
Aug 21, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Gretchen L GierachMark E Sherman
Oct 3, 2014·Journal of the National Cancer Institute·Jonine D FigueroaMark E Sherman
Citations
Jan 7, 2016·BMJ Open·Stéphane JoostIdris Guessous
Dec 23, 2017·International Journal of Molecular Sciences·Andrea ManniHenry Thompson
May 11, 2018·BMC Medical Imaging·Natalia PartainRoshni Rao
Jan 4, 2020·Annals of Surgical Oncology·Christina A MinamiMelissa L Pilewskie
Jul 14, 2017·Breast Cancer Research and Treatment·Aliya AlimujiangAdetunji T Toriola
Mar 19, 2020·International Journal of Environmental Research and Public Health·Rachel McFarland LuciaHannah Lui Park
Aug 6, 2020·Journal of Clinical Medicine·Eun Young KimSeungho Ryu
May 28, 2019·Breast Cancer Research and Treatment·Natalie J EngmannKarla Kerlikowske
Feb 28, 2020·Cancer Prevention Research·Yunan HanAdetunji T Toriola
Jun 22, 2018·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kirsti Vik HjerkindGiske Ursin
Jul 13, 2017·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Stacey E AlexeeffLaurel A Habel
Aug 3, 2018·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Giovanna MasalaDomenico Palli
Jun 13, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Natalie J EngmannCeline M Vachon
Jun 13, 2021·Epigenetics : Official Journal of the DNA Methylation Society·Rachel M LuciaHannah Lui Park
Jul 3, 2021·Cancers·Emma C AtakpaMichelle Harvie
Sep 17, 2021·Breast Cancer Research and Treatment·Yoosun ChoSeungho Ryu