The effect of chlorhexidine irrigation of the bladder in the rat.

British Journal of Urology
W E Harper, L R Matz

Abstract

Rats' bladders were irrigated with aqueous solutions of chlorhexidine digluconate 1 : 5,000 or 1 : 10,000 for varying periods up to 48 hours. Histologic examination of the bladders showed severe erosive cystitis in a high percentage of cases. It is concluded that chlorhexidine cannot be recommended for prolonged irrigation of the bladder or for instillation during the intermittent catheterisation where chlorhexidine has repeated and prolonged contact with bladder mucosa.

References

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Citations

May 1, 1982·World Journal of Surgery·G D Chisholm
Dec 1, 1976·British Journal of Urology·W E Harper, L R Matz
Apr 1, 1978·British Journal of Urology·J C Brocklehurst, S Brocklehurst
Jul 15, 1987·American Journal of Ophthalmology·L M HamedE M Helveston
Oct 1, 1988·Urology·P J SmithW A Gillespie
Oct 1, 1981·British Journal of Urology·W E Harper
Mar 1, 1982·Acta paediatrica Scandinavica·H S Aabech, E N Lien
Oct 1, 1989·British Journal of Urology·T S ElliottK Woodhouse

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