PMID: 9546936Jan 1, 1996Paper

The effect of cigarette smoking on exercise capacity in patients with intermittent claudication

Vascular Medicine
A W Gardner

Abstract

The purposes of this study were: (1) to determine whether peripheral arterial occlusive disease (PAOD) patients who smoked had more severe claudication pain, reduced peripheral circulation, and poorer cardiopulmonary measurements at peak exercise than non-smoking patients, and (2) to determine whether the differences between the smoking and non-smoking patients persisted after controlling for the resting ankle/brachial systolic pressure index (ABI). Thirty-eight PAOD patients (ABI = 0.59 +/- 0.15, mean +/- SD) who smoked an average of 1.5 packs of cigarettes per day over 42 years and 100 PAOD patients (ABI = 0.74 +/- 26) who had quit smoking for an average of 7 years were recruited. Smokers refrained from smoking on the day of testing. Claudication pain times, oxygen uptake, ventilation, leg oximetry, and ankle systolic pressure responses to peak exercise were recorded. The smoking group had more severe claudication pain, as maximal pain occurred 1:37 min:s sooner during exercise (p < 0.05), and the pain took 2:21 min:s longer to subside (p < 0.01) compared to the non-smoking group. Additionally, at peak exercise the smoking group had a lower oxygen uptake (12.8 +/- 2.6 vs 13.9 +/- 2.4 ml/kg/min, p < 0.01), a higher ventilation...Continue Reading

References

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Citations

Jul 23, 1999·Medicine and Science in Sports and Exercise·A W GardnerL A Killewich
May 3, 2000·The British Journal of Surgery·K H TanP R Edwards
Jun 8, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·A S RyanA W Gardner
May 9, 2001·Current Treatment Options in Cardiovascular Medicine·Alan T. Hirsch, Laura M Reich
Jun 23, 2001·The Journal of Cardiovascular Nursing·S K ChristmanJ Buckworth
Jun 24, 2006·Wiener klinische Wochenschrift·Afshin AssadianMichael Kunze
Jul 29, 2006·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Serena Tonstad, J Andrew Johnston
Jan 27, 2011·Current Treatment Options in Cardiovascular Medicine·Elizabeth V Ratchford, James H Black
Sep 13, 2006·The Journal of Cardiovascular Nursing·Roberta K Oka
Nov 20, 2008·Angiology·K J DickinsonS Homer-Vanniasinkam
Nov 6, 2013·Journal of Cardiopulmonary Rehabilitation and Prevention·Raphael Mendes Ritti-DiasAndrew W Gardner
Apr 1, 2006·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Renzhe CuiTakashi Shimamoto
Aug 1, 2001·The Physician and Sportsmedicine·A W Gardner
Aug 16, 2018·Journal of Vascular Surgery·Christopher R WilliamsBenjamin S Brooke
Nov 14, 2020·Journal of Cardiopulmonary Rehabilitation and Prevention·Cindy H NguyenSusan Marzolini

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