The effect of comorbid illness on mortality outcomes in cardiac surgery

Archives of Surgery
Robert A CloughGerald T O'Connor

Abstract

Comorbid conditions are associated with the risk of death from coronary artery bypass graft surgery. Prospective cohort study data were collected on patient and disease characteristics and comorbid conditions including hypertension, diabetes, obesity, vascular disease, chronic obstructive pulmonary disease, cancer (excluding nonmelanoma skin cancer), dialysis-dependent renal failure, liver disease, and dementia. Statistical analysis used logistic regression for the calculation of adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Regional cardiac surgery database. A total of 27,239 consecutive patients undergoing isolated coronary artery bypass graft surgery. In-hospital mortality rate. The prevalence of comorbid conditions was as follows: hypertension, 64.3%; diabetes, 30.1%; obesity, 24.6%; severe obesity, 7.2%; vascular disease, 18.3%; chronic obstructive pulmonary disease, 10.9%; peptic ulcer, 7.5%; cancer, 3.8%; renal failure, 1.5%; liver disease, 0.6%; and dementia, 0.1%. After adjustment for patient and disease characteristics, including age, sex, previous cardiac surgery, priority of surgery, degree of left main coronary stenosis, number of diseased coronary arteries, and left ventricular ejection fraction, ...Continue Reading

Citations

Dec 5, 2012·ISRN Cardiology·Harold L Lazar
Jan 27, 2007·Current Diabetes Reports·Bruce J Leavitt
Jun 27, 2003·Journal of Cardiothoracic and Vascular Anesthesia·Tiberiu EzriBeniamin Medalion
Dec 5, 2002·Surgery·Emily V A FinlaysonDavid E Wennberg
Jan 11, 2013·Clinical and Experimental Hypertension : CHE·Nevena KalezicVladan Zivaljevic
Oct 10, 2015·Journal of Neurosurgery. Spine·Michael D CusimanoGabriela Ilie
Jan 26, 2016·The Journal of Thoracic and Cardiovascular Surgery·Paul Kurlansky
Sep 11, 2012·The American Journal of Medicine·Robert M ReedSteven Scharf
Dec 11, 2003·Chest·Argyris S MichalopoulosSpyros D Mentzelopoulos
May 26, 2009·The Journal of Thoracic and Cardiovascular Surgery·Aslan T TurerJohn H Alexander
Jun 21, 2005·International Journal of Clinical Practice·G I VarugheseG Y H Lip
Feb 11, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Daniel A CulverUNKNOWN CCF Lung Transplant Group
Oct 9, 2004·Annales Françaises D'anesthèsie Et De Rèanimation·C GirardUNKNOWN Anesthésie-Réanimation-Techniques en Chirurgie Cardiaque
Sep 25, 2004·American Heart Journal·Charmaine E LokJack V Tu
Apr 24, 2015·ANZ Journal of Surgery·Tinghan YangZiqiang Wang
Apr 26, 2006·Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation·Willis H NavarroJ Douglas Rizzo
Oct 22, 2016·Journal of Neurosurgery·Michael D CusimanoGabriela Ilie
Mar 21, 2017·Revista clínica española·M Bernabeu-WittelM Ollero-Baturone
Feb 13, 2018·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Yosuke NakadateThomas Schricker
Sep 1, 2005·The American Journal of Gastroenterology·Mark T Keegan, David J Plevak
Apr 5, 2019·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Kefeng ZhangRuopeng An
Feb 22, 2017·The Open Cardiovascular Medicine Journal·Aristotle D Protopapas
Apr 6, 2004·Critical Care Medicine·Richard A Wiklund
Jan 16, 2021·Journal of Cardiac Surgery·Clancy W MullanArnar Geirsson
Jun 1, 2021·The Journal of Thoracic and Cardiovascular Surgery·Mevlüt ÇelikAd J J C Bogers
Jul 6, 2006·Circulation·Bruce J LeavittUNKNOWN Northern New England Cardiovascular Disease Study Group

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