Abstract
This study sought to determine the effect of contact force (CF) on atrial lesion size, quality, and transmurality by using a chronic porcine model of radiofrequency ablation. CF is a major determinant of ventricular lesion formation, but uncertainty exists regarding the most appropriate CF parameters to safely achieve permanent, transmural lesions in the atria. Intercaval linear ablation (30 W, 42°C, 17 ml/min irrigation) was performed in 8 Göttingen minipigs by using a force-sensing catheter with CF >20 g (high force) or <10 g (low force) at alternate ends of the line, separated by an intentional gap. Voltage mapping and cardiovascular magnetic resonance (CMR) imaging were performed pre-ablation, immediately after ablation, and at 2 months' post-procedure. Lesions were sectioned orthogonal to the axis of ablation to assess transmurality. Mean CF was 22.6 ± 11.4 g and 7.8 ± 4.0 g in the high and low CF regions. Acute tissue edema was greater with high CF, both caudally (7.0 mm vs. 4.6 mm; p = 0.016) and cranially (6.9 mm vs. 4.6 mm; p = 0.038). There was no difference in chronic lesion size (voltage mapping) or volume (late gadolinium enhancement CMR) between high and low CF regions. There was no difference in scar density (ass...Continue Reading
References
Dec 3, 1998·Journal of Cardiovascular Electrophysiology·O J EickB Schumacher
Sep 18, 1999·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·H H PetersenS Haunso
Jan 5, 2001·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·X ZhengR E Ideker
May 7, 2002·Pacing and Clinical Electrophysiology : PACE·Christian WeissStephan Willems
Oct 12, 2005·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Niels StagegaardJesper Hastrup Svendsen
Feb 1, 2006·Hypertension·David J KennedyJoseph I Shapiro
Apr 1, 2008·Journal of Cardiovascular Electrophysiology·Yasuo OkumuraDouglas L Packer
Sep 23, 2008·Journal of Cardiovascular Electrophysiology·Thomas H EverettJeffrey E Olgin
Oct 8, 2009·Circulation. Arrhythmia and Electrophysiology·Katsuaki YokoyamaWarren M Jackman
Jan 12, 2010·Pacing and Clinical Electrophysiology : PACE·Joyce MengWarren J Manning
Apr 7, 2010·Journal of Cardiovascular Electrophysiology·Dipen C ShahGiovanni Leo
Nov 19, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Dipen ShahBeat Walpoth
Jan 21, 2011·Circulation. Arrhythmia and Electrophysiology·Francesco PernaMoussa Mansour
Jun 2, 2012·Circulation. Arrhythmia and Electrophysiology·Aruna ArujunaJaswinder Gill
Jul 24, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Vivek Y ReddyKarl-Heinz Kuck
Jan 16, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Patricia TungMark E Josephson
Mar 22, 2013·Circulation. Arrhythmia and Electrophysiology·Petr NeuzilKarl-Heinz Kuck
Jan 15, 2014·European Heart Journal·James L HarrisonMark D O'Neill
Mar 13, 2014·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Rashed KarimKawal S Rhode
Aug 16, 2014·Journal of the American College of Cardiology·Andrea NataleFrancis E Marchlinski
Nov 9, 2014·Circulation. Arrhythmia and Electrophysiology·Atsushi IkedaWarren M Jackman
Dec 3, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Stephen G QuallichPaul A Iaizzo
Dec 30, 2014·Journal of Cardiovascular Electrophysiology·Julian W E JarmanTom Wong
Citations
May 20, 2018·Journal of Cardiovascular Electrophysiology·Samuel ThomasRavi Ranjan
Apr 15, 2018·Circulation. Arrhythmia and Electrophysiology·John WhitakerMark D O'Neill
Jan 10, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Tom De PotterEdward Duncan
Apr 28, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Louisa O'NeillSteven E Williams
Sep 27, 2018·Journal of Cardiovascular Electrophysiology·Henry ChubbMark O'Neill
Oct 31, 2018·Journal of Cardiovascular Electrophysiology·Kennosuke YamashitaRavi Ranjan
Jan 10, 2020·Journal of Cardiovascular Electrophysiology·Kennosuke YamashitaRavi Ranjan
Apr 17, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Mikkel Giehm-ReeseJens Cosedis Nielsen
Apr 24, 2020·Journal of Cardiovascular Electrophysiology·Fabrizio R AssisHarikrishna Tandri
Aug 8, 2020·Journal of Cardiovascular Electrophysiology·Mark D O'Neill, Steven E Williams
Jul 21, 2017·Expert Review of Medical Devices·Tilman Maurer, Karl-Heinz Kuck
Dec 4, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Louisa O'NeillSteven E Williams
Jan 30, 2018·Journal of Cardiovascular Electrophysiology·Mark O'Neill, Steven E Williams
Nov 25, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Christian Sohns, Philipp Sommer
May 8, 2021·Heart, Lung & Circulation·Thirakan RattanakositRajiv Mahajan