The effect of daily intake of green coffee bean extract as compared to Agiolax® on the alveolar bone of albino rats

Dental and Medical Problems
Marwa Magdy Saad Abbass, Dalia Abdel-Hameed El-Baz

Abstract

Obesity is a worldwide medical problem in which excess body fat is accumulated in the body. The use of weight loss supplements such as green coffee bean extract and Agiolax has become a common trend among people who want to lose weight in a fast and non-tiring way. As a result of their effect on fluid excretion, both of these products may be expected to have a damaging effect on the alveolar bone. The aim of the present study was to evaluate the histopathalogical effect of green coffee bean extract as compared to Agiolax on the alveolar bone of albino rats. Twenty-seven adult male albino rats were randomly assigned to 3 groups. Nine received distilled water daily for 2 months by oral gavage (the control group); the other 2 groups received 1 mg/100 g body weight green coffee bean extract or Agiolax 8 mg/100 g body weight daily for 2 months by oral gavage (the GC and Ag groups, respectively). The alveolar bones were dissected and examined histologically, histomorphometrically and by western blotting. The bone area percentage and the calcium level in serum were significantly decreased in the GC and Ag groups, while the calcium level in urine was significantly increased in both the experimental groups as compared to the control gro...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.