The effect of daily treatment with an olive oil/lanolin emollient on skin integrity in preterm infants: a randomized controlled trial

Pediatric Dermatology
Ursula Kiechl-KohlendorferRomy Inzinger

Abstract

To date, appropriate skin therapy for premature infants has not been clearly defined. Emollient creams are often used without solid evidence for a benefit to the neonate. The aim of the current study was to investigate the cutaneous effects of two different topical ointment therapies. Between October 2004 and November 2006 we prospectively enrolled 173 infants between 25 and 36 weeks of gestation admitted to a neonatal intensive care unit. Infants were randomly assigned to daily topical treatment with water-in-oil emollient cream (Bepanthen), olive oil cream (70% lanolin, 30% olive oil), or to a control group. Each neonate was continuously treated for a maximum of 4 weeks. Skin condition (skin score reflecting degree of dermatitis) in these groups was compared at weeks 1, 2, 3, and 4. Neonates treated with olive oil cream showed statistically less dermatitis than did neonates treated with emollient cream, and both had a better outcome than those in the control group (p < 0.001 in weeks 2-4). Treatment effects persisted throughout the study period and applied to infants of all gestational ages. This study demonstrates that topical skin therapy lowers the risk of dermatitis. Olive oil cream was superior to water-in-oil emollient ...Continue Reading

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Citations

Dec 1, 2009·Maternal and Child Health Journal·Ayten Sentürk ErenelRabiye Erenoğlu
Feb 24, 2016·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Anne BrowerCatherine Burns
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Apr 9, 2013·Journal for Specialists in Pediatric Nursing : JSPN·Carmen AlonsoJose I Emparanza
Jul 29, 2015·Poultry Science·Darin C BennettKimberly M Cheng
Nov 22, 2014·Nursing and Midwifery Studies·Mohsen Adib-HajbagheryMahdi Mashaiekhi
Jul 9, 2014·Orvosi hetilap·Zsanett Renáta CsomaMiklós Szabó
Apr 19, 2015·Clinics in Dermatology·Marty O VisscherMauricio Odio
Sep 28, 2016·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Deanna E Johnson
Aug 20, 2017·Archives of Disease in Childhood·David Richard Thaxter, Anna Kilonback
Aug 29, 2018·Pediatric Dermatology·Theodora K KaragounisKimberly D Morel
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Jan 30, 2016·The Cochrane Database of Systematic Reviews·Jemma Cleminson, William McGuire
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Mar 1, 2019·Global Pediatric Health·Rebecca VongsaCorey Cunningham
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Dec 16, 2020·Neonatal Network : NN·Jodi Herron BehrRebecca L Casarez
Feb 6, 2021·The Cochrane Database of Systematic Reviews·Maeve M KelleherRobert J Boyle
May 8, 2021·The Cochrane Database of Systematic Reviews·Jemma Cleminson, William McGuire

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