The Effect of Demodex Infestation on Blepharitis and the Ocular Symptoms

Eye & Contact Lens
Naciye KabataşCanan Gürdal

Abstract

This study aimed to determine the frequency of Demodex infestation of eyelashes in patients with and without blepharitis and to determine the effects of Demodex infestation on blepharitis and the ocular symptoms. The study included patients with chronic mixed (anterior + posterior) blepharitis who presented to our clinic. Patients with refractive error and no ocular disease were enrolled as the control group. From each participant, a total of 4 eyelashes were removed and were then examined under a light microscope for Demodex infestation. Symptoms, fluorescein tear breakup time, and ocular surface staining pattern were recorded. The prevalence of Demodex infection in the blepharitis group was 67.2%, versus 54.9% in the control group (P=0.18). The incidence of itching in the blepharitis group was significantly higher in the Demodex (+) patients than in the Demodex (-) patients (P<0.001). Fluorescein tear breakup time in the Demodex (+) patients was significantly shorter than in the Demodex (-) patients (P<0.001). There was not a significant difference in the fluorescein staining pattern between the 2 groups (P=0.57). The incidence of advanced stage blepharitis was significantly higher among the Demodex (+) patients (P=0.007). Th...Continue Reading

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Citations

Jan 31, 2018·International Ophthalmology·Orla MurphyAoife Lloyd-McKernan
Jun 7, 2019·Cornea·Idan HechtIgor Kaiserman
Jun 27, 2018·Eye & Contact Lens·Abdullah Kaya, Canan Gürdal
Nov 15, 2019·Cornea·Pinnita PrabhasawatAnupong Veeraburinon
Jul 22, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Alexis Ceecee ZhangLaura E Downie
Apr 6, 2019·Eye & Contact Lens·Orla MurphyAoife Lloyd-McKernan
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May 29, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Marcel Y ÁvilaCarolina Rizo Madrid
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Aug 2, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Roberto González SalinasHugo Quiroz-Mercado

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