PMID: 7537588Apr 1, 1995Paper

The effect of dextran 40 on patency following severe trauma in small arteries and veins

British Journal of Plastic Surgery
L SalemarkP Dougan

Abstract

Arteriotomy/intimectomy and venotomy/intimectomy were performed in the rabbit ear. Low molecular-weight dextran (dextran 40) was infused 2 h before reperfusion and on postoperative days 1, 3 and 5 using a standard clinical protocol. Bleeding-times at reperfusion were recorded and patencies determined at intervals up to 2 weeks. Rabbits given single preoperative bolus doses of saline were used as controls. Dextran significantly prolonged bleeding-times in arteries and significantly improved early patency in both types of vessel, but the enhancements disappear by one week. Dextran 40 infusion thus has little effect on long-term patency.

References

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Citations

Mar 5, 2003·Microsurgery·N Jallali
Sep 1, 1996·British Journal of Plastic Surgery·I G Grishin, A I Krupatkin
Jun 8, 2001·Critical Care Medicine·E de Jonge, M Levi
Dec 18, 2001·Plastic and Reconstructive Surgery·M H Conrad, W P Adams
Jan 9, 2010·Plastic and Reconstructive Surgery·Christopher J SalgadoSamir Mardini
Jun 3, 2008·Asian Cardiovascular & Thoracic Annals·Arvind Kohli, Gurjit Singh
Dec 14, 2004·Vascular and Endovascular Surgery·Farshad AbirBauer E Sumpio
Jun 9, 2006·Microsurgery·Hung-Chi ChenStefano Spanio
Jul 11, 2006·Acta Biotheoretica·Christopher W Pawlowski
Jan 1, 1996·Basic Research in Cardiology·L Hove-MadsenR Fischmeister
Aug 2, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Marie GeorgetRodolphe Fischmeister

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