The effect of dietary soy intake on weight loss, glycaemic control, lipid profiles and biomarkers of inflammation and oxidative stress in women with polycystic ovary syndrome: a randomised clinical trial

Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association
Maryam KaramaliZatollah Asemi

Abstract

The present study aimed to evaluate the effects of dietary soy intake on weight loss and metabolic status of patients with polycystic ovary syndrome (PCOS). A randomised clinical trial was conducted among 60 women with PCOS. Participants were randomly assigned into two groups to receive either a test diet (n = 30) or a control diet (n = 30) for 8 weeks. Participants in the test group consumed a diet containing 0.8 g protein kg-1 body weight (35% animal proteins, 35% soy protein and 30% vegetable proteins) and participants in the control group consumed a similar diet containing 70% animal proteins and 30% vegetable proteins. Adherence to the test diet, compared with the control diet, resulted in significant decreases [mean (SD)] in body mass index (BMI) [-0.3 (0.6) versus +0.1 (0.5) kg m-2 , P = 0.02], fasting plasma glucose [-0.2 (0.5) versus +0.1 (0.3) mmol L-1 , P = 0.01], total testosterone [-0.3 (0.7) versus +0.3 (0.3) mmol L-1 , P < 0.001], insulin [-15.0 (18.0) versus +4.8 (18.6) pmol L-1 , P < 0.001] and insulin resistance [-0.6 (0.6) versus +0.2 (0.7), P < 0.001], as well as a significant increase in quantitative insulin sensitivity check index [+0.01 (0.01) versus -0.002 (0.02), P = 0.01]. In addition, significant decr...Continue Reading

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Citations

Feb 14, 2020·PloS One·Madison ParkerMarie Barnard
Jun 24, 2020·The Cochrane Database of Systematic Reviews·Karaponi Am Okesene-GafaCaroline A Crowther
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Aug 17, 2020·Journal of Occupational and Environmental Medicine·Sadeel A Shanshal, Harith Kh Al-Qazaz
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Jul 28, 2020·Antioxidants·Gianluca Rizzo
Jun 3, 2021·Nutrients·Sadia AfrinMostafa A Borahay

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