The effect of donor age and low-dose gamma irradiation on the initial biomechanical properties of human tibialis tendon allografts

The American Journal of Sports Medicine
Laura L GreavesCharles H Brown

Abstract

Most tissue banks recover and irradiate tibialis tendon allografts from donors aged up to 65 years. It is unknown whether donor age and low-dose gamma irradiation affect the initial biomechanical properties of tibialis allografts. Donor age up to 65 years and low-dose gamma irradiation do not significantly affect the initial biomechanical properties of tibialis allografts. Controlled laboratory study. One hundred twenty-six tibialis tendon allografts (63 pairs, 37 human donors) were divided into 3 age groups: young (<45 years), middle (46-55 years), and old (56-65 years). Within each age group, half of the paired tendons underwent tensile testing as single-strand grafts and the other half as double-strand grafts. One tendon from each donor pair was randomly assigned to undergo terminal sterilization with an absorbed dose of 1.46 to 1.80 Mrad (14.6-18.0 kGy) gamma irradiation, whereas the other tendon received no irradiation. All tendon grafts were preconditioned with a cyclic load and tested to failure in tension. Irradiated single-strand tendons in the old age group had a longer displacement at failure compared to the middle but not the young age group. Nonirradiated double-strand tendons in the old age group had a lower failu...Continue Reading

References

Feb 1, 1979·Mechanisms of Ageing and Development·A Viidik
Jan 1, 1975·Clinical Orthopaedics and Related Research·F G GirgisA Monajem
Mar 1, 1991·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·M J GibbonsF R Noyes
Nov 1, 1993·The American Journal of Sports Medicine·D E CooperR F Warren
Nov 1, 1995·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·A SalehpourA Ratcliffe
Mar 1, 1996·Clinical Orthopaedics and Related Research·D W JacksonT M Simon
Mar 1, 1996·The American Journal of Sports Medicine·C T VangsnessT M Moore
Feb 1, 1996·Journal of Biomechanical Engineering·C W SmithJ N Kearney
Jan 1, 1996·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·H U StäubliL P Nolte
Jun 3, 1998·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·B D Beynnon, A A Amis
Sep 3, 1999·The Orthopedic Clinics of North America·S Stevenson
Oct 14, 2000·The American Journal of Sports Medicine·J BrandD L Johnson
Jul 5, 2002·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Tammy L Haut DonahueColin Gregersen
May 17, 2003·The American Journal of Sports Medicine·C Thomas VangsnessTillman M Moore
Jun 27, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C R RussoL Ferrucci
Jun 27, 2003·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·J NylandJ Couch
Aug 28, 2003·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Jürgen HöherAndreas Weiler
Dec 16, 2003·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Albert W PearsallZachary Scheer
Jul 21, 2004·The American Journal of Sports Medicine·Andrew R CurranArnold D Scheller
Dec 14, 2004·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Sung-Jae KimSang-Wook Ryu
Nov 26, 2005·Cell and Tissue Banking·Thomas F BakerSimon Bogdansky
Nov 3, 2007·The American Journal of Sports Medicine·David R McAllisterC Thomas Vangsness

❮ Previous
Next ❯

Citations

Mar 16, 2012·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Lovro SuhodolčanJanez Brecelj
May 18, 2013·Cell and Tissue Banking·E M H GardnerP J Yates
Aug 8, 2012·Orthopedics·Daniel M HamptonJohn J Klimkiewicz
Dec 17, 2014·Advanced Drug Delivery Reviews·A J LomasD I Zeugolis
Aug 16, 2015·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·M Tyrrell BurrusDavid R Diduch
Feb 24, 2015·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Michael R BonielloKevin F Bonner
Nov 19, 2014·The American Journal of Sports Medicine·Katherine R SwankJason L Dragoo
Mar 30, 2017·Clinical Orthopaedics and Related Research·Drew A LansdownBernard R Bach
Feb 8, 2013·The American Journal of Sports Medicine·Adam B YankeBernard R Bach
Jan 2, 2009·The American Journal of Sports Medicine·John J EliasWilliam J Ciccone
May 10, 2016·World Journal of Radiology·Rita SinghAntaryami Singh
Nov 11, 2010·The American Journal of Sports Medicine·Robby S SikkaC Thomas Vangsness
Aug 5, 2017·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Nicoletta GaglianoPietro Randelli
Aug 22, 2014·The Journal of Bone and Joint Surgery. American Volume·Egleide Y Elenes, Shawn A Hunter
Jan 8, 2020·Orthopaedic Journal of Sports Medicine·Adam J BeerRachel M Frank
Sep 11, 2020·Scientific Reports·Benjamin FischerStefan Schleifenbaum
Oct 7, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Laura de GirolamoSusanna Chubinskaya
Oct 7, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Andreas M Seitz, Lutz Dürselen
Mar 18, 2016·The Journal of Bone and Joint Surgery. American Volume·Aristides I CruzJ Todd R Lawrence

❮ Previous
Next ❯

Methods Mentioned

BETA
irradiating

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Related Papers

Aǧrı : Ağrı (Algoloji) Derneği'nin Yayın organıdır = The journal of the Turkish Society of Algology
Selçuk Peker, Meriç Sengöz
© 2022 Meta ULC. All rights reserved