The effect of electrical stimulation on lumbar spinal fusion in older patients: a randomized, controlled, multi-center trial: part 2: fusion rates

Spine
Thomas AndersenCody E Bünger

Abstract

Randomized, controlled, multi-center trial. To investigate the effect of direct current (DC) electrical stimulation on fusion rates after lumbar spinal fusion in patients older than 60 years. Older patients have increased complication rates after spinal fusion surgery. Treatments which have the possibility of enhancing functional outcome and fusion rates without lengthening the procedure could prove beneficial. DC-stimulation of spinal fusion has proven effective in increasing fusion rates in younger and "high risk" patients, but little information exist on the effect in older patients. A randomized clinical trial comprising 5 orthopedic centers. The study included a total of 107 patients randomized to uninstrumented posterolateral lumbar spinal fusion with or without DC-stimulation. Fusion rate was assessed at 2 year follow-up using thin slice CT. Functional outcome was assessed using Dallas Pain Questionnaire and Low Back Pain Rating Scale pain index. RESULTS.: Available follow-up after 2 years was 89% (84 of 95 patients). Fusion rates were surprisingly low. DC-stimulation had no effect on fusion rate: 35% versus 36% in controls. Other factors associated with low fusion rates were female gender (32% vs. 42% in males, P = 0.05...Continue Reading

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Citations

Apr 30, 2010·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Thomas AndersenCody Bünger
Aug 25, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Lisa Gregersen OestergaardFinn Bjarke Christensen
Sep 3, 2013·The Spine Journal : Official Journal of the North American Spine Society·Nai F TianYong L Chi
Jun 7, 2018·Scientific Reports·Thomas Wyss BalmerPhilippe Büchler
Aug 15, 2017·JBJS Reviews·Jack M HaglinAlan H Daniels
Mar 16, 2017·Journal of Neurosurgery. Spine·Marcella MaderaUNKNOWN for the Seton Spine Rehabilitation Study Group
Jun 16, 2015·The Cochrane Database of Systematic Reviews·Mark I JohnsonKathleen A Sluka
Apr 8, 2019·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Mit Balvantray BhavsarJohn H Barker
Mar 27, 2021·Journal of Occupational and Environmental Medicine·Kurt T HegmannJeffrey S Harris
Sep 30, 2021·Global Spine Journal·Ravi S NunnaJens R Chapman

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