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The effect of environmental pH on glycosaminoglycan metabolism by normal human chondrocytes

The Journal of Laboratory and Clinical Medicine

Feb 1, 1976

Elliott R SchwartzRobert Charles Thompson

PMID: 1453

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Abstract

The synthesis and release of sulfated glycosaminoglycans by normal human chondrocytes in culture are markedly affected by environmental pH. The biosynthetic rate is increased threefold as the pH of the growth medium is raised from 7.0 to 8.0. This coincides with a corresponding elevatio...read more

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Hydrogen-Ion Concentration
Sulfates, Inorganic
Proteoglycan Type H
Glycosaminoglycans
Cytochemistry
Structure of Articular Cartilage
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  • The effect of environmental pH on glycosaminoglycan metabolism by normal human chondrocytes

    The Journal of Laboratory and Clinical Medicine

    Feb 1, 1976

    Elliott R SchwartzRobert Charles Thompson

    PMID: 1453

    DOI:

    Abstract

    The synthesis and release of sulfated glycosaminoglycans by normal human chondrocytes in culture are markedly affected by environmental pH. The biosynthetic rate is increased threefold as the pH of the growth medium is raised from 7.0 to 8.0. This coincides with a corresponding elevatio...read more

    Mentioned in this Paper

    Hydrogen-Ion Concentration
    Sulfates, Inorganic
    Proteoglycan Type H
    Glycosaminoglycans
    Cytochemistry

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