The effect of ethnicity on the prevalence of diabetes and associated chronic kidney disease

QJM : Monthly Journal of the Association of Physicians
G DreyerM M Yaqoob

Abstract

The effect of ethnicity on the prevalence of diabetes mellitus (DM) and associated chronic kidney disease (CKD) is unknown. To establish the impact of ethnicity on the prevalence and severity of diabetes mellitus and associated CKD. Cross-sectional study of 34 359 adult diabetic patients in three primary care trusts in the UK. Read coded data from general practice computers was used to analyse the relationship between ethnicity, DM and CKD. The prevalence of DM was 3.5% for Whites, 11% for South Asians and 8% for Black groups. The prevalence of CKD (stages 3-5) among diabetics was 18%. CKD stage 3 was more prevalent in Whites compared to South Asians--OR 0.79 (95% CI: 0.71-0.87) and Blacks--OR 0.49 (95% CI: 0.43-0.57). Among all CKD patients severity (CKD stages 4, 5) was associated with Black (OR 1.39, 95% CI: 1.06-1.81) and South Asian (OR 1.54, 95% CI: 1.26-1.88) ethnicity compared to Whites. Less than 50% of diabetics with CKD met the target blood pressure (BP) of 130/80 mmHg. The prevalence of a blood pressure > 150/90 mmHg in diabetics with CKD was South Asian 15.6%, White 13.9%, Black 21.8% (P < 0.001). Proteinuria was present in 8.6% of all diabetic patients. However, this increased to 18.6% in patients with CKD, and wa...Continue Reading

References

Oct 8, 1999·The New England Journal of Medicine·E Ritz, S R Orth
Sep 22, 2001·The New England Journal of Medicine·B M BrennerUNKNOWN RENAAL Study Investigators
Nov 21, 2002·JAMA : the Journal of the American Medical Association·Jackson T WrightUNKNOWN African American Study of Kidney Disease and Hypertension Study Group
Dec 25, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Josef CoreshAndrew S Levey
Jun 24, 2003·Journal of the American Society of Nephrology : JASN·Steven J ChadbanRobert C Atkins
Oct 22, 2003·Journal of the American Society of Nephrology : JASN·Chi-Yuan HsuMichael G Shlipak
Nov 18, 2004·The Annals of Pharmacotherapy·Harita R PatelLaura E Hall
Apr 21, 2005·Kidney International·Jacobien C VerhaveUNKNOWN PREVEND Study Group
Apr 19, 2007·Kidney International·P E StevensC K T Farmer
Sep 25, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Michael P QuinnDamian G Fogarty
Jan 25, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Obidiugwu Kenrik DuruKeith Norris
Feb 26, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Fatiu A Arogundade, Rashad S Barsoum
Apr 11, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Adam T Whaley-ConnellUNKNOWN Kidney Early Evaluation Program Investigators
Apr 19, 2008·BMJ : British Medical Journal·Alison Frater

❮ Previous
Next ❯

Citations

May 5, 2010·Nature Reviews. Nephrology·Anne-Emilie Declèves, Kumar Sharma
Jul 2, 2010·The New England Journal of Medicine·Tom von SternbergNancy McClure
Apr 7, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sean J BarbourAdeera Levin
Dec 12, 2012·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Simon D S FraserDon Nutbeam
Aug 6, 2011·QJM : Monthly Journal of the Association of Physicians·D S Grimes
May 31, 2011·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Rohini MathurJohn Robson
May 31, 2011·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Sally A HullKambiz Boomla
Apr 9, 2013·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Clive SealeMoira Kelly
Aug 21, 2013·Indian Journal of Endocrinology and Metabolism·Sarita BajajKomal Verma
Feb 5, 2013·Primary Health Care Research & Development·Ellena BadrickJohn Robson
Mar 20, 2014·Current Cardiology Reports·Arti Shah, Alka M Kanaya
Nov 28, 2013·Journal of Public Health·Simon D S FraserDonal O'Donoghue
Aug 20, 2015·Journal of Clinical Medicine·Vasantha Muthu Muthuppalaniappan, Muhammad Magdi Yaqoob
Jul 26, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Paul J RoderickJohn Wright
Oct 23, 2015·The Lancet. Diabetes & Endocrinology·Naveed Sattar, Jason M R Gill
Dec 25, 2015·Singapore Medical Journal·Eng Sing Lee, Wern Ee Tang
Jun 23, 2009·Diabetic Medicine : a Journal of the British Diabetic Association·S M ChoudhuryR Williams
May 19, 2011·Diabetes/metabolism Research and Reviews·Sara D Garduño-Diaz, Santosh Khokhar
Mar 1, 2012·Journal of Renal Care·John Dean
Apr 23, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·G DreyerM M Yaqoob
Sep 5, 2015·BMC Research Notes·Lasantha S MalavigeJonathan C Levy
Jul 26, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Alexander KainzRainer Oberbauer
May 5, 2010·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Jaime A DavidsonJeffrey A Jackson
Aug 24, 2016·Journal of Immigrant and Minority Health·Sumathi VenkateshLorraine J Weatherspoon
Jul 2, 2014·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Sally HullMuhammad Magdi Yaqoob
Dec 3, 2014·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Sally HullJohn Robson
May 26, 2018·Circulation·Annabelle Santos VolgmanUNKNOWN American Heart Association Council on Epidemiology and Prevention; Cardiovascular Disease and Stroke in Women and Special Po
Nov 26, 2009·Current Opinion in Lipidology·Deepak Bhatnagar
Mar 14, 2019·Journal of Diabetes·Anoop MisraKaushik L Ramaiya
May 19, 2017·Clinical Science·Aline Silva MirandaAna Cristina Simões E Silva
Mar 1, 2015·Expert Review of Endocrinology & Metabolism·Jayne Smith-PalmerJay P Bae
Mar 25, 2021·World Journal of Diabetes·Tahseen A Chowdhury
Sep 17, 2021·Journal of Diabetes Investigation·Jun-Sing WangUNKNOWN Diabetes Kidney Disease Research Committee of the Diabetes Association of the Republic of China (Taiwan)

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.