The effect of exercise training on the pulmonary arterial system in patients with pulmonary hypertension

Progress in Cardiovascular Diseases
Ross ArenaJonathan Myers

Abstract

Given the unique and clinically ominous pathology associated with pulmonary arterial (PA) hypertension (PH) and its implications for the eventual deterioration of right ventricular function, exercise training (ET) was historically not recommended. More recently, a body of literature demonstrating the safety and efficacy of ET in PH has emerged. The primary focus of this review is to provide a synopsis of current evidence assessing the effects of ET on the PA system in patients with PH. The current body of evidence is relatively small and it is not clear if ET improves PA function or vessel characteristics. Nevertheless, studies have consistently found ET leads to numerous clinically relevant benefits including increased: 1) aerobic capacity, 2) muscle strength, 3) exercise tolerance, and 4) quality of life. Thus, ET, given its clinical benefits, is likely to enjoy increased utilization in patients with PH.

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Citations

Nov 17, 2015·Progress in Cardiovascular Diseases·Ross ArenaMarco Guazzi
Oct 16, 2015·Basic Research in Cardiology·Daniel Moreira-GonçalvesTiago Henriques-Coelho
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Apr 26, 2019·Journal of Cardiopulmonary Rehabilitation and Prevention·Cemal OzemekRoss Arena
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Jun 18, 2018·Heart Failure Reviews·Paulien VinkeKlaske van Norren
May 26, 2018·Expert Review of Respiratory Medicine·Abraham Samuel BabuJonathan Myers

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