The effect of extended-hours hemodialysis on outcomes: A systematic review and meta-analysis.

Hemodialysis International
Katherine L HullJames O Burton

Abstract

Extended-hours hemodialysis is associated with improvements in quality of life (QoL) and mortality, but it may accelerate the loss of residual kidney function (RKF) and increase vascular access complications. Multiple established databases were systematically searched; randomized and non-randomized studies were pooled separately. QoL outcomes were assessed using standardized mean difference (SMD), vascular access adverse events and mortality were assessed with relative risk ratios (RR). Four hundred seventy-six patients from six trials were eligible. Data from randomized controlled trials (RCTs) could only be synthesized for vascular access adverse events and mortality, which demonstrated no significant change in vascular access adverse events (RR 1.25, 95% CI 0.88 to 1.77) or mortality (RR 2.29, 95% CI 0.60 to 8.71). Pooled data from non-randomized trials demonstrated no significant difference in QoL (SF-36 Physical Component Summary SMD 0.61, 95% CI -0.10 to 1.31, SF-36 Mental Component Summary SMD -0.04, 95% CI -0.61 to 0.54). RKF was assessed in one report which demonstrated a potential reduction over 12 months with extended-hours hemodialysis. The majority of trials had high risk of bias. Extended-hours hemodialysis was no...Continue Reading

References

Jun 30, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·D SheminL D Dworkin
Sep 29, 2001·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·R M LindsayUNKNOWN Daily/Nocturnal Dialysis Study Group
May 25, 2002·Kidney International·Christopher T ChanAndreas Pierratos
Jun 28, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Robert M LindsayUNKNOWN London Daily/Nocturnal Hemodialysis Study
Jun 28, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A Paul HeidenheimRobert M Lindsay
Apr 5, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rachel L PerlmanRajiv Saran
Sep 1, 2005·Journal of Advanced Nursing·Joanne Cleary, Jonathan Drennan
Sep 20, 2007·JAMA : the Journal of the American Medical Association·Bruce F CulletonBraden J Manns
Dec 26, 2008·Kidney International·Braden J MannsUNKNOWN Alberta Kidney Disease Network
Dec 19, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Eduardo LacsonRaymond M Hakim
Mar 1, 2012·Journal of the American Society of Nephrology : JASN·Eduardo LacsonRaymond M Hakim
Mar 1, 2012·Journal of the American Society of Nephrology : JASN·Gihad E NesrallahRita S Suri
Mar 1, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Paweena SusantitaphongBertrand L Jaber
Sep 29, 2012·Hemodialysis International·Steven G AchingerJuan Carlos Ayus
Oct 6, 2012·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Min JunVlado Perkovic
Jan 25, 2013·Kidney International·John T DaugirdasUNKNOWN FHN Trial Group
Feb 9, 2013·Journal of the American Society of Nephrology : JASN·Rita S SuriUNKNOWN Frequent Hemodialysis Network Trial Group
Jun 7, 2014·Blood Purification·Tom CornelisJeroen P Kooman
Nov 28, 2015·Clinical Kidney Journal·Matthew P M Graham-BrownJames O Burton
Feb 13, 2016·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Yoshitsugu ObiKamyar Kalantar-Zadeh
Oct 25, 2016·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Peter A McCulloughGeorge L Bakris
Oct 25, 2016·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Michael A KrausJohn M Burkart
Jan 18, 2017·Kidney International·Amit X GargUNKNOWN Frequent Hemodialysis Network Trial Investigators
Feb 6, 2017·Journal of the American Society of Nephrology : JASN·Meg J JardineUNKNOWN Paul
Apr 1, 2017·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ben WongRobert P Pauly
Jan 20, 2018·Canadian Journal of Kidney Health and Disease·Anna MathewGihad Nesrallah
Aug 21, 2018·Current Opinion in Nephrology and Hypertension·James O Burton, Matthew P M Graham-Brown
Oct 4, 2018·Current Opinion in Nephrology and Hypertension·James O Burton, Matthew P M Graham-Brown
Oct 26, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Raja Mohammed Kaja KamalEnric Vilar

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