The effect of extracorporeal shock wave lithotripsy on the rat spinal cord

Spinal Cord
A KaratasB Can

Abstract

Experimental study. To determine the effects of extracorporeal shock wave lithotripsy (ESWL) on the rat spinal cord. Animals were randomly divided into three groups. Groups 1 and 2 consisted of five rats each that underwent ESWL (2000 impulses at 15 kV and 2000 impulses at 18 kV, respectively) and group 3 contained five control rats (no shock wave treatment). ESWL-treated and control rats were compared with regard to light and electron microscopic findings of the adjacent spinal cord. Gross neurological outcomes were normal in all groups. Light microscopic examination of group 1 showed extensive extravasation of red blood cells over all the interstitial spaces. Group 2 also had haemorrhagic areas and an irregular organization of axons in the white matter. Transmission electron microscopic examination of group 1 indicated extravasated red blood cells through the endothelium and swollen axoplasm, degenerated mitochondria, destruction of myelin sheaths and a slight increase in the number of lysosomes. Extravasated red blood cells were also seen in group 2. The axoplasmic mitochondria were enlarged, but no sign of mitochondrial degeneration was observed. Lamellar degeneration of myelin sheaths and abundant lysosomes were more predo...Continue Reading

References

Feb 1, 1992·The Journal of Urology·C WeberG W Drach
Mar 1, 1989·The Journal of Urology·D L McCulloughE G Furr
Jan 1, 1987·Urology·R C NewmanB Finlayson
Feb 1, 1987·Urology·R NewmanB Finlayson
Jun 1, 1995·Paraplegia·L Tosi, G Terrini
Feb 23, 2000·Experimental Neurology·J L RidetL Schwartz
Apr 23, 2005·The Journal of Comparative Neurology·Minodora O Totoiu, Hans S Keirstead

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