PMID: 9556171Apr 29, 1998Paper

The effect of follow-up on limiting non-participation bias in genetic epidemiologic investigations

European Journal of Epidemiology
P A RomittiT L Burns

Abstract

The use of a comprehensive follow-up strategy to limit non-participation bias was evaluated in a population-based case-control study of orofacial clefts. Birth parents were requested to provide exposure data, and index children and parents were asked to provide blood specimens. Follow-up included telephone or postal reminders every two weeks for up to three months. Consent to participate was received from 281 (76.6%) case mothers and 246 (72.4%) case fathers. The corresponding totals for controls were 279 (54.7%) and 245 (49.8%). Evaluation of participation rates by intensity of follow-up showed that 23% of case and 18% of control families consented without reminders (first stage); 81% of cases and 83% of controls agreed following one or two reminders (second stage); and the remainder of participants consented following three or more reminders (final stage). Cumulative distributions of sociodemographic characteristics differed little between second and final stage participants. Odds ratios for maternal multivitamin use were similar between second and final stage participants, whereas those for maternal and paternal smoking tended to decline. Although follow-up measures were necessary to enroll most families, use of more than tw...Continue Reading

Citations

May 26, 2006·Journal of Dental Research·A ModestoA C Lidral
Jun 28, 2008·International Journal of Epidemiology·Candice Y Johnson, Julian Little
Sep 28, 2013·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Jill GlidewellKrista S Crider
Nov 8, 2006·American Journal of Medical Genetics. Part a·Joseph R AvilaJeffrey C Murray
May 12, 2011·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Lucy WilliamsJonathan Sandy
Jul 4, 2003·Paediatric and Perinatal Epidemiology·Danelle T LobdellPauline Mendola
Oct 7, 2008·American Journal of Medical Genetics. Part a·Alexandre R VieiraJeffrey C Murray
Dec 6, 2005·PLoS Genetics·Alexandre R VieiraJeffrey C Murray
Oct 21, 2009·Paediatric and Perinatal Epidemiology·Roy M NilsenPer Magnus

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.