The effect of fusafungine on post-operative pain and wound healing after pediatric tonsillectomy

International Journal of Pediatric Otorhinolaryngology
Yucel AkbasDeniz Micozkadioglu

Abstract

To investigate the effect of fusafungine spray on pain and healing process after pediatric tonsillectomy. Sixty children with ages between 4 and 14 years underwent tonsillectomy or adenotonsillectomy. The patients were randomly divided into three groups and each group consisted of 20 patients. Group 1 was treated with antibiotic (amoxicillin-clavulanic acid) plus analgesic (acetaminophen), group 2 was treated with fusafungine plus analgesic (acetaminophen) and group 3 was treated with only fusafungine. The average ages were 7.8 + 3.4, 6.6 + 2.9, and 8.2 + 3.7 for groups 1, 2, and 3, respectively. Clinical evaluations were made after the operation on the 1st (T1), 3rd (T3), 7th (T7), 10th (T10), and 14th days (T14). There was no significant difference in post-operative pain between study groups on the post-operative 1st, 3rd, and 7th days (P > 0.05), a statistically significant difference was present between groups 1 and 3, and groups 1 and 2 on the post-operative 10th and 14th day (P = 0.018 and 0.037, respectively). Pain was less in groups 2 and 3 than in group 1 on the 10th and 14th day. Also there was a significant difference in healing time of the tonsillary beds between groups 1 and 2, and groups 1 and 3 on the 10th and 14...Continue Reading

References

Nov 1, 1992·The Laryngoscope·S B Freeman, J K Markwell
Jun 1, 1986·Archives of Otolaryngology--head & Neck Surgery·S A TelianW P Potsic
Feb 14, 1997·International Journal of Pediatric Otorhinolaryngology·A H Messner, J A Barbita
Feb 5, 1998·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·D A Randall, M E Hoffer
Jun 7, 2003·International Journal of Pediatric Otorhinolaryngology·Irfan Kaygusuz, Nihat Susaman

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Citations

Apr 29, 2006·Advances in Therapy·Köksal YucaMuzaffer Kiris
Apr 16, 2011·Analytical and Bioanalytical Chemistry·Lada IvanovaSilvio Uhlig
Feb 28, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Muthuswamy DhiwakarWilliam S McKerrow
Nov 14, 2013·Anesthesiology and Pain Medicine·Peyman BoroumandFatemeh Aarabi Moghaddam
Sep 27, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Abdulmonem Al-Layla, Tareq M Mahafza
Aug 18, 2006·International Journal of Pediatric Otorhinolaryngology·Samet OzlugedikAli Titiz
Jan 12, 2010·Acta otorrinolaringológica española·Sergio ObesoCarlos Suárez
Dec 18, 2013·Toxicology Mechanisms and Methods·Lara ManyesGuillermina Font
Nov 20, 2016·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·A LalA Chakravarti
Apr 18, 2018·Clinical and Experimental Otorhinolaryngology·Jeong Hwan MoonSang Joon Lee
Oct 6, 2018·The Journal of Laryngology and Otology·N H DavidossP L Santa Maria
Jul 1, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Mohammad FaramarziSareh Roosta

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