The effect of glucagon on barium-enema examination

J C MeeroffJ I Isenberg


Fifty barium-enema studies were performed with glucagon and 50 with a placebo to compare their effect on colonic spasm, patient discomfort, and diagnostic quality. Each drug was administered in a randomized double-blind fashion and was injected intramuscularly 10 minutes before beginning the enema. Bowel relaxation during fluoroscopy was graded. Patients were questioned about discomfort during and immediately after the enema, and radiographs were reviewed blindly for diagnostic quality and degree of spasm. Studies done with glucagon produced significantly less spasm and discomfort and better diagnostic quality compared to the placebo (p less than 0.01).


Jun 1, 2000·Radiology·S E RubesinH Herlinger
Apr 1, 1976·The British Journal of Radiology·K C Simpkins
Jan 1, 1982·Gastrointestinal Radiology·G A Mandell, S K Teplick
Jan 30, 1979·Gastrointestinal Radiology·R E MillerR L Brunelle
Dec 17, 2008·Expert Review of Gastroenterology & Hepatology·Rizwan Aslam, Judy Yee
Nov 3, 2009·Journal of the American College of Radiology : JACR·Elizabeth G McFarlandAmerican College of Radiology
Mar 4, 2008·Gastroenterology Clinics of North America·Susan SummertonMitchell S Cappell
Dec 1, 1979·Journal of Pediatric Surgery·G M Haase, E T Boles
May 16, 2007·Radiologic Clinics of North America·Luis A LanderasJudy Yee
Dec 1, 1977·Journal of Pediatric Surgery·G R HoyE T Boles
Jul 1, 1979·Current Problems in Diagnostic Radiology·F A Mettler
May 1, 1982·Drug Intelligence & Clinical Pharmacy·B G Bryant, D J Trout

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