PMID: 4029492Jan 1, 1985Paper

The effect of glucagon on N-acetylglutamate-synthetase

The International Journal of Biochemistry
G Banko, H Zollner


The effect of glucagon and the protein content of the diet on the activity of N-acetylglutamate synthetase was studied. The activity of N-acetylglutamate synthetase depended on the protein content of the diet. Glucagon increased the activity of N-acetylglutamate synthetase and reduced the stimulatory effect of arginine. The enzyme of glucose-fed animals became arginine independent. It was concluded that glucagon induced some kind of covalent modification of the synthetase.


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