The effect of heart rate on coronary plaque measurements in 320-row coronary CT angiography

The International Journal of Cardiovascular Imaging
Masafumi KidohYasuyuki Yamashita

Abstract

Repeatability of quantitative assessment of atherosclerotic plaques is important for the accurate detection of high-risk plaques in coronary CT angiography (CTA). We assessed the effect of heart rate (HR) on plaque CT number using a coronary artery model and a cardiac phantom capable of simulating cardiac motion. The coronary artery model with luminal stenosis on a cardiac phantom was imaged with a simulated HR of 0, 50, 60, and 70 beats per minute using a 320-row CT scanner. We reconstructed CT images for cardiac diastolic phases (for 75% R-R interval) using filtered back projection (FBP), hybrid iterative reconstruction (AIDR3D), and model-based iterative reconstruction (FIRST). Two observers measured plaque attenuation in the lesion with 75% stenosis. The coefficient of determination (R2) was obtained to evaluate interobserver agreement. At HR 70, FIRST improved the correlation between two observers compared with FBP and AIDR3D (FIRST: R2 = 0.68, p < 0.05; FBP: R2 = 0.29, p = 0.31; AIDR3D: R2 = 0.22, p = 0.18). These R2 at HR 70 were lower compared with at HR 50 (FIRST: R2 = 0.92, p < 0.05; FBP: R2 = 0.83, p < 0.05; AIDR3D: R2 = 0.87, p < 0.05) and HR 0 (FIRST: R2 = 0.97, p < 0.05; FBP: R2 = 0.89, p < 0.05; AIDR3D: R2 = 0.95...Continue Reading

References

Nov 22, 2007·AJR. American Journal of Roentgenology·Harald SeifarthRoman Fischbach
Nov 29, 2008·The New England Journal of Medicine·Julie M MillerJoão A C Lima
Jun 27, 2009·Journal of the American College of Cardiology·Sadako MotoyamaJagat Narula
Aug 12, 2009·The International Journal of Cardiovascular Imaging·Philip A AraozCynthia H McCollough
Feb 2, 2010·Journal of Computer Assisted Tomography·Yutaka TanamiSachio Kuribayashi
May 1, 2010·Journal of Cardiovascular Computed Tomography·Stephan AchenbachMohamed Marwan
Jun 15, 2010·International Journal of Cardiology·Toshiro KitagawaYasuki Kihara
Sep 8, 2010·The International Journal of Cardiovascular Imaging·Maiken Glud DalagerHans Erik Bøtker
Apr 4, 2015·Journal of the American College of Cardiology·Leslee J ShawY Chandrashekhar
Aug 19, 2015·The International Journal of Cardiovascular Imaging·Bálint SzilveszterPál Maurovich-Horvat
Feb 20, 2016·Circulation Research·Jason M TarkinJames H F Rudd

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Citations

Jan 12, 2021·Journal of Cardiovascular Computed Tomography·Mohammed N MeahDamini Dey

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