Abstract
Both diabetes and hemodialysis (HD) are associated with increased oxidative stress. The aim of this study was to clarify the effect of maintenance HD on oxidative stress parameters in diabetic patients and to explore any relation between carotid artery intima-media thickness (CIMT) and oxidative stress markers. Twenty Type 2 diabetic patients undergoing chronic maintenance HD, 20 type 2 diabetic patients with normal renal function, and 20 age- and sex-matched healthy subjects were included. Serum thiobarbituric acid reactive substances (TBARS), protein carbonyl content (PCO), and nitrite/nitrate levels were determined as oxidative stress markers. Serum vitamin E, plasma sulfhydryl (P-SH), erythrocyte glutathione (GSH) levels, and superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) activities were measured as antioxidants. CIMT was assessed by carotid artery ultrasonography. Both diabetic patient groups had enhanced oxidative stress indicated by higher levels of TBARS, PCO, and nitrate/nitrite and lower activities of SOD, CAT, and GPx compared to controls. Diabetic patients undergoing HD had significantly higher CIMT (P=.001) and higher levels of nitrite/nitrate (P=.05), PCO (P=.03), and GSH (P=.04) but ...Continue Reading
References
Dec 1, 1992·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M M HirschlK Derfler
Jun 1, 1992·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·K W MaL Raij
Sep 15, 1990·BMJ : British Medical Journal·M A McMillanB J Junor
Apr 1, 1988·Atherosclerosis·A PoliR Paoletti
Jan 1, 1986·Annals of the Rheumatic Diseases·J F KosterA J Swaak
Mar 28, 1974·The New England Journal of Medicine·A LindnerB H Scribner
Jan 1, 1984·Methods in Enzymology·I D Desai
Sep 1, 1995·Kidney International·T KawagishiH Morii
Nov 1, 1993·Stroke; a Journal of Cerebral Circulation·A KaderR R Trifiletti
Mar 1, 1995·Stroke; a Journal of Cerebral Circulation·G L BurkeG Heiss
Jan 1, 1994·Methods in Enzymology·A Z Reznick, L Packer
Aug 1, 1996·Kidney International·G M LondonF Metivier
Jun 1, 1997·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M KochB Grabensee
Oct 7, 1997·Circulation·M L BotsD E Grobbee
May 29, 1998·Circulation·P W WilsonW B Kannel
Nov 20, 1998·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·P W Wilson
Dec 22, 1998·The American Journal of Cardiology·H C McGill, C A McMahan
Jan 8, 1999·The New England Journal of Medicine·D H O'LearyS K Wolfson
May 11, 1999·Circulation·J BlacherG M London
Sep 27, 2000·Journal of the American Society of Nephrology : JASN·Masahisa FujisawaSeiya Okuda
Sep 30, 2000·Artificial Organs·R Hojs
Oct 30, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·A KlemmG Stein
Feb 28, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Marion MorenaBernard Canaud
Sep 27, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Marta TodeschiniMarina Noris
Dec 13, 2002·Clinical Chemistry and Laboratory Medicine : CCLM·Evrim DursunGülsen Yakupoglu
Jul 25, 2003·Biochimica Et Biophysica Acta·Birgit MayerKarl Oettl
Oct 18, 2003·Clinical Biochemistry·Shweta BhatiaKrishna Madhava Prabhu
Oct 30, 2003·Journal of Diabetes and Its Complications·Saliha Apakkan AksunOya Bayindir
Nov 6, 2003·JAMA : the Journal of the American Medical Association·Olli T RaitakariJorma S A Viikari
Jan 1, 1952·Acta Pathologica Et Microbiologica Scandinavica·J GLAVINDH DAM
Jul 29, 2005·Artificial Organs·Robert EkartBreda Pecovnik Balon
Nov 1, 2005·Acta Diabetologica·E DursunT Ozben
Oct 20, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Andrzej KraśniakWładysław Sulowicz
Citations
Feb 9, 2011·Seminars in Dialysis·Lucia Del VecchioMarina Carini
Oct 30, 2010·Chinese Medicine·Roy Chi-Yan ChoiKarl Wah-Keung Tsim
May 3, 2011·Circulation Journal : Official Journal of the Japanese Circulation Society·Masahiro NatsuakiTakeshi Kimura
Aug 24, 2012·PloS One·Sonia LópezJose Manuel Soria
Jan 20, 2012·The Journal of Nutrition·Yumie TakataUlrike Peters
Dec 21, 2013·Journal of Diabetes and Metabolic Disorders·Mona H El SamahyNermeen A Kamal
May 3, 2011·Renal Failure·Ambar KhairaSanjay K Agarwal
Oct 2, 2012·Diabetes Research and Clinical Practice·Krystyna PawlakDariusz Pawlak
Jan 1, 2014·Echocardiography·Burak AltunFatma Uysal
Mar 15, 2016·International Heart Journal·Hideki YagiMasami Murakami
Jun 13, 2015·Journal of Diabetes Research·Anna TavridouVassilis Vargemezis
Oct 23, 2012·European Journal of Pharmacology·Supriya KadianPitchai Balakumar
Mar 21, 2012·The Journal of International Medical Research·M Yusuf AlsagaffY Tomino
May 24, 2011·Molecular Biology Reports·B González-DiezP Muñiz
Mar 20, 2010·Current Opinion in Pediatrics