Abstract
BACKGROUND Gastrointestinal (GI) bleeding is one of the most prevalent internal medical emergencies. Despite using several methods of treatment, effective treatment cannot be achieved in some patients. Hemostasis powder® is a mineral-herbal product. This emulsion was able to coagulate blood in, in vitro studies and also was effective in the treatment of mucosal and cutaneous bleeding in animal studies, without any toxicity. We decided to compare its effect on the treatment of human GI bleeding with the other common method for treatment of GI bleeding "argon plasma coagulation plus epinephrine injection" in a pilot randomized clinical trial. METHODS The patients with GI bleeding who were admitted to the emergency wards of Ghaem and Imam-Reza Hospitals in Mashhad were randomized to treatment with Hemostasis powder® or "argon plasma coagulation plus epinephrine injection" method, with randomized doctors, after complete testimonial sheet. The patients underwent re-endoscopy to evaluate the ulcers 3 days later, and were under observation for 3 months. After achieving the number of patients that was planned (20 patients), all data were entered to SPSS software version 20 and were analyzed with parametric and non-parametric tests. RES...Continue Reading
References
Oct 19, 2002·The American Journal of Gastroenterology·James D LewisBrian L Strom
Sep 17, 2005·Scandinavian Journal of Gastroenterology·Christian OhmannChristian Reinhold
Apr 1, 2006·The American Journal of Gastroenterology·Annmarie LassenOve B Schaffalitzky de Muckadell
Jun 15, 2007·Gut·Joseph J Y SungJames Y W Lau
Feb 2, 2008·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Viviane AdamBarkun N Alan
Aug 30, 2008·The New England Journal of Medicine·Ian M GralnekMarc Bardou
Jan 20, 2010·Annals of Internal Medicine·Alan N BarkunUNKNOWN International Consensus Upper Gastrointestinal Bleeding Conference Group
Mar 9, 2011·Endoscopy·S A GidayA N Kalloo
Apr 2, 2011·Endoscopy·J J Y SungS A Giday
Oct 31, 2012·Endoscopy·S NahonUNKNOWN Groupe des Hémorragies Digestives Hautes de l’ANGH
Apr 30, 2013·Gastrointestinal Endoscopy·Sarah LeblancFrédéric Prat
Feb 7, 2014·Canadian Journal of Gastroenterology & Hepatology·Alan Hoi Lun YauRobert Allan Enns
Aug 19, 2014·World Journal of Gastrointestinal Pathophysiology·Marco Bustamante-Balén, Gema Plumé
Oct 18, 2016·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Mousalreza HosseiniHassan Rakhshandeh
Oct 18, 2016·Journal of Gastroenterology and Hepatology·Mohammad MinakariVahid Sebghatollahi
Oct 21, 2016·Endoscopy·Sami HaddaraEmmanuel Coron
Mar 24, 2018·Journal of Pediatric Gastroenterology and Nutrition·Mike ThomsonDalia Belsha