The effect of herbal extracts in an experimental mouthrinse on established plaque and gingivitis

Journal of Clinical Periodontology
G A Van der WeijdenU van der Velden

Abstract

The purpose of the present study was to establish in vitro the inhibiting effect of a herbal extract mixture on a selected number of micro-organisms and to test in vivo the effect of a mouthwash containing 6.3 mg/ml herbal extract mixture on plaque and gingivitis as compared to a minus active control mouthrinse. The herbal extract was a mixture of: Juniperus communis (juniper), Urtica dioca (nettle), Achillaea millefolium (yarrow); 1:1:1. In the study, in-vitro, the effect of pure herbal extract mixture on acid production of Streptococcus mutans was tested and the minimum inhibitory concentrations (MIC) of the following micro-organisms were tested: Streptococcus mutans, Streptococcus mitis, Actynomyces viscosus, Actynomyces naeslundii, Actinobacillus actinomycetemcomitans, Prevotella intermedia, Campylobacter rectus, Fusobacterium nucleatum, Veillonella parvula. The MIC-values for A. viscosus and P. gingivalis were 100 mg/ml. The MIC-values for A. naeslundii and A. actinomycetemcomitans were considerably lower (10 mg/ml). S. mitis was the most susceptible of the tested organisms to the extract with a MIC value of 1 mg/ml. S. mutans, C. rectus, V. parvula, and F. nucleatum were not influenced by the extracts. No inhibitory effec...Continue Reading

References

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Oct 1, 1994·Journal of Clinical Periodontology·G A Van der WeijdenU Van der Velden
Feb 1, 1994·Journal of Clinical Periodontology·G A van der WeijdenU van der Velden

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Citations

Jul 19, 2013·Clinical Oral Investigations·Yong ChenC Jayampath Seneviratne
Jun 21, 2003·Journal of Periodontology·Alexander PistoriusMatthias Kreislert
Jul 4, 2012·Journal of Applied Microbiology·J SmullenH A Foster
Apr 20, 2011·Periodontology 2000·Nitish Surathu, Arun V Kurumathur
May 13, 2004·Journal of Ethnopharmacology·Jittra LimsongJintakorn Kuvatanasuchati
Sep 25, 2004·The Journal of the American Dental Association·Sean S LeeYiming Li
Feb 15, 2019·Proceedings. Mathematical, Physical, and Engineering Sciences·Federica CuomoC Alberto Figueroa
Aug 26, 2014·Journal of Complementary & Integrative Medicine·Kavita HotwaniKrishna Sharma
Feb 13, 2020·BMC Complementary Medicine and Therapies·Chandrashekar JanakiramBruce A Dye

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