PMID: 1187194Jan 1, 1975Paper

The effect of hypotensive drugs (Serpasil) on the histochemical reactions in the small intestine of white rats.

Pathologia Europaea
I Królikowska-Prasal, J S Tarach

Abstract

The influence of Serpasil (Ciba) on histological activities of dehydrogenases and reductases as well as on PAS-positive substances in the small intestine of white rats has been studied. It has been demonstrated that a decrease in the succinic, lactic and glucose-6-phosphate dehydrogenase activities as well as in the NADH and NADPH tetrazole reductase activities occurs in the rat's small intestine epithelial cells after the administration of Serpasil. However, a considerable intensification in the reactions to PAS-positive substances in the mucous cells and an increase in the amount of these cells has been observed.

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