The effect of hypothermia on adnexal torsion/detorsion injury in a rat ovary model

Journal of Pediatric Surgery
Erdal TürkAhmet Güven

Abstract

Much attention has been given to hypothermia as it is effective in inhibiting inflammatory responses and also ischemia/reperfusion injury. Therefore, the aim of this study was to evaluate the effect of hypothermia on torsion/detorsion injury in rats. Twenty-eight rats were randomly divided into four groups of sham-operated (SG), adnexal torsion/detorsion group (TG), adnexal torsion/detorsion+hypothermia group (THG) and hypothermia group (HG). In the SG group, right ovaries were excised after 3-h fixation to abdominal wall. In the TG, right adnexal underwent 720° torsion in a counterclockwise direction for 3h and then excised after 3-h detorsion period. In the THG, after 3-h torsion period, ovaries were immediately subjected to hypothermia (4°C) for 30-min and they were excised after 3-h detorsioned period. In the HG, the right ovaries were subjected to hypothermia for 30-min and excised after 3-h fixation period. One half of each ovary was immediately stored for antioxidant enzyme activity and tissue lipid peroxidation. The remainder was fixed for histopathological examination. Adnexal torsion and detorsion significantly increased the tissue level of Malondialdehyde, Superoxide dismutase and Reduced glutathione. On the other ha...Continue Reading

References

Jan 1, 1991·Free Radical Biology & Medicine·D Armstrong, F al-Awadi
Apr 1, 1988·Transplantation·F O Belzer, J H Southard
Oct 1, 1974·The Journal of Clinical Investigation·M L Salin, J M McCord
Jan 15, 2002·American Journal of Physiology. Cell Physiology·Chuanyu Li, Robert M Jackson
Nov 16, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Onder CelikSaim Yologlu
Oct 14, 2005·The New England Journal of Medicine·Seetha ShankaranUNKNOWN National Institute of Child Health and Human Development Neonatal Research Network
Jul 18, 2006·Liver International : Official Journal of the International Association for the Study of the Liver·Matthias BehrendsClaus U Niemann
Aug 4, 2006·Clinical Obstetrics and Gynecology·Gabriel Oelsner, David Shashar
Aug 2, 2008·Expert Review of Neurotherapeutics·Simon NagelAlastair M Buchan
Oct 7, 2008·The Journal of Obstetrics and Gynaecology Research·Figen Kir SahinSadik Buyukbas
Apr 21, 2009·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Mehmet KaracaOsman N Keles
Sep 9, 2009·Journal of Pediatric Surgery·Philippe GalinierPhilippe Vaysse
Jun 26, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Yasar ErgunErdogan Aslan
Nov 3, 2010·Journal of Pediatric Surgery·Deniz Cemgil ArikanAyhan Coskun
Jan 11, 2011·Urology·Fayez AlmodhenMohamed T El-Sherbiny
Mar 27, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Mustafa KaraOzgul Tap
Sep 15, 2012·Journal of Pediatric Surgery·Mustafa Kemal AslanMurat Çakmak
Feb 28, 2013·Current Protein & Peptide Science·Jong-Heon KimKyoungho Suk
Jun 26, 2013·International Journal of Surgery·Muhammet Erdal SakTalip Gul
Jul 31, 2013·Acta Cirúrgica Brasileira·Emanuel Burck dos SantosCarlos Otávio Corso

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