The effect of in vivo and in vitro irradiation (25 Gy) on the subsequent in vitro growth of satellite cells

Cell and Tissue Research
P E MozdziakR G Cassens

Abstract

The effect of in vivo and in vitro irradiation on subsequent satellite cell growth, in vitro, was investigated to ascertain the ability of a 25 Gy dose to inhibit satellite cell proliferation. Satellite cells were isolated from the left (irradiated) and right (non-irradiated) Pectoralis thoracicus of two-week-old tom turkeys 16 h (n=3) and seven weeks (n=2) after the left Pectoralis thoracicus had been irradiated (25 Gy). Satellite cells isolated from the irradiated and non-irradiated muscles exhibited similar (P>0.10) in vitro proliferation indicating that a population of satellite cells survived an in vivo dose of 25 Gy. In additional experiments, satellite cell cultures derived from tom turkey Pectoralis thoracicus were irradiated (25 Gy) in vitro. The number of satellite cells did not (P>0.05) increase in irradiated cultures for 134 h following irradiation, while satellite cells in non-irradiated cultures proliferated (P<0.05) over this time. At later time periods, satellite cell number increased (P<0.05) in irradiated cultures indicating that a population of satellite cells survived irradiation. The results of these in vitro experiments suggest that a 25 Gy dose of irradiation does not abolish satellite cell divisions in t...Continue Reading

Citations

Jan 9, 2009·Pflügers Archiv : European journal of physiology·Karen J B MartinsCharles T Putman
Jan 13, 2006·Cell and Tissue Research·Paul E MozdziakJames N Petitte
Jan 11, 2007·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Gregory R Adams
Sep 9, 1999·In Vitro Cellular & Developmental Biology. Animal·J A UlibarriT M Best
Nov 28, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·C T PutmanD Pette
Aug 19, 2000·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·P Mozdziak, E Schultz
May 1, 2007·Archives of Physical Medicine and Rehabilitation·Richard M LoveringPatrick G De Deyne
Mar 6, 2003·Developmental Dynamics : an Official Publication of the American Association of Anatomists·P E MozdziakJ N Petitte
Mar 8, 2012·Journal of Tissue Engineering and Regenerative Medicine·Xiaorong MaFang Chen
Dec 11, 1999·Developmental Dynamics : an Official Publication of the American Association of Anatomists·K BlaveriJ E Morgan
May 2, 2002·The Journal of Nutrition·Paul E MozdziakDarell W McCoy
Sep 13, 2002·American Journal of Physiology. Cell Physiology·Gregory R AdamsKenneth M Baldwin
Aug 6, 2020·Animals : an Open Access Journal From MDPI·Maurycy JankowskiBartosz Kempisty
Feb 1, 1997·The American Journal of Physiology·P E MozdziakR G Cassens

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.