The effect of inlet and outlet boundary conditions in image-based CFD modeling of aortic flow

Biomedical Engineering Online
Sudharsan Madhavan, Erica M Cherry Kemmerling

Abstract

Computational modeling of cardiovascular flow is a growing and useful field, but such simulations usually require the researcher to guess the flow's inlet and outlet conditions since they are difficult and expensive to measure. It is critical to determine the amount of uncertainty introduced by these assumptions in order to evaluate the degree to which cardiovascular flow simulations are accurate. Our work begins to address this question by examining the sensitivity of flow to several different assumed velocity inlet and outlet conditions in a patient-specific aorta model. We examined the differences between plug flow, parabolic flow, linear shear flows, skewed cubic flow profiles, and Womersley flow at the inlet. Only the shape of the inlet velocity profile was varied-all other parameters were identical among these simulations. Secondary flow in the form of a counter-rotating pair of vortices was also added to parabolic axial flow to study its effect on the solution. In addition, we examined the differences between two-element Windkessel, three element Windkessel and the outflow boundary conditions. In these simulations, only the outlet boundary condition was varied. The results show axial and in-plane velocities are considera...Continue Reading

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Citations

Mar 7, 2019·International Journal for Numerical Methods in Biomedical Engineering·Huanming XuJiang Xiong
Apr 10, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Johannes TögerPer-Olof Persson
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Jan 20, 2021·International Journal for Numerical Methods in Biomedical Engineering·Alena Jonášová, Jan Vimmr
Apr 20, 2021·Computational and Mathematical Methods in Medicine·M Conijn, G J Krings
Jun 10, 2021·BMC Research Notes·Amirtahà TaebiEmilie Roncali
Jun 19, 2021·Frontiers in Cardiovascular Medicine·Lauren JohnstonAsimina Kazakidi
Aug 23, 2021·Biomedical Engineering Online·Romana PerinajováSaša Kenjereš

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Methods Mentioned

BETA
rheology

Software Mentioned

ANSYS Fluent
HeartFlow
ANSYS® Academic Research [
ANSYS
ANSYS®

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