PMID: 22569622May 10, 2012Paper

The effect of intracuff alkalinized 2% lidocaine on emergence coughing, sore throat, and hoarseness in smokers

Revista da Associação Médica Brasileira
Laís Helena Camacho NavarroNorma Sueli Pinheiro Módolo

Abstract

We evaluated whether endotracheal tube (ETT) intracuff alkalinized lidocaine was superior to saline in blunting emergence coughing, postoperative sore throat, and hoarseness in smokers. In our prospective, double-blind trial, we enrolled 50 smoking patients undergoing surgery under general anesthesia including nitrous oxide (N2O). Patients were randomly allocated to receive either ETT intracuff 2% lidocaine plus 8.4% sodium bicarbonate (L group), or ETT intracuff 0.9% saline (S group). The ETT cuff was inflated to achieve a cuff pressure that prevented air leak during positive pressure ventilation. Incidence of emergence coughing, sore throat, and hoarseness were analyzed. The volume of inflation solution, the intracuff pressure, the duration of anesthesia, the time elapsed to extubation after discontinuation of anesthesia, and the volume of the inflation solution and the air withdrawn from the ETT cuff were also recorded. Intracuff alkalinized 2% lidocaine was superior to saline in blunting emergence coughing (p < 0.001). The incidence of sore throat was significantly lower in the L group at the post-anesthesia care unit (PACU) (p = 0.02). However, at 24 hours after extubation, sore throat incidence was similar in both groups ...Continue Reading

Associated Clinical Trials

References

Dec 1, 1985·Anesthesia and Analgesia·H YukiokaM Fujimori
Mar 1, 1997·Acta Anaesthesiologica Scandinavica·B SchwilkM Georgieff
Mar 17, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·C J HuangT T Wei
Jan 8, 2000·São Paulo Medical Journal = Revista Paulista De Medicina·J R BrazP Nascimento Júnior
Jun 1, 2000·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·W HirotaK Hirota
Jan 5, 2002·Anesthesia and Analgesia·Jean-Pierre EstebeClaude Ecoffey

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