PMID: 11331638May 2, 2001Paper

The effect of intracytoplasmic sperm injection and semen parameters on blastocyst development in vitro

Human Reproduction
J E Miller, T T Smith

Abstract

The present study compares the development and quality of blastocysts derived from conventional oocyte insemination with those derived from intracytoplasmic sperm injection (ICSI). Oocytes were collected from patients undergoing ovarian stimulation with human menopausal gonadotrophins for IVF. Patients with normal semen were assigned to conventional oocyte insemination while those with progressive motility <20% and/or normal sperm morphology < or =4% were assigned to ICSI. Resulting embryos were cultured for up to 6 days. The mean number and percentage of embryos reaching the blastocyst stage and the mean number and percentage of blastocysts of high quality on days 5-6 were assessed for both treatment groups and compared. The influence of paternal factors (sperm concentration, motility, progressive motility, morphology) on blastocyst development and quality were assessed by regression analyses. Significantly more ICSI-derived embryos arrested at the 5- to 8-cell stage (P = 0.024) concomitant with the activation of the paternal genome than those derived from conventional oocyte insemination. Significantly fewer ICSI-derived embryos reached the blastocyst stage on days 5-6 (P<0.001) and significantly fewer ICSI-derived embryos we...Continue Reading

References

Sep 1, 1992·Human Reproduction·M E EnginsuJ P Geraedts
Aug 1, 1992·Human Reproduction·L SantellaB Dale
Jun 1, 1992·Human Reproduction·Y MenezoB Nicollet
Jan 1, 1992·Journal of Reproduction and Fertility·D Y Liu, H W Baker
Jan 1, 1988·Fertility and Sterility·T F KrugerS Oehninger
Dec 5, 1980·Science·D P EvensonM R Melamed
May 1, 1994·Molecular Reproduction and Development·L Janny, Y J Menezo
Nov 1, 1993·Fertility and Sterility·J ParinaudG Richoilley
Jul 1, 1993·Human Reproduction·A C Van SteirteghemP Devroey
Dec 12, 1997·Molecular Human Reproduction·R G Edwards, H K Beard
Apr 21, 1998·Journal of Assisted Reproduction and Genetics·A H Sathananthan
Oct 21, 1999·Human Reproduction·L A Van Der WesterlakenN Naaktgeboren
Oct 26, 1999·The Journal of Experimental Zoology·A Ahmadi, S C Ng
Jan 13, 2000·Fertility and Sterility·M BlakeJ Cohen
Jun 30, 2000·Human Reproduction·T A GriffithsM Herbert

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Citations

Jul 29, 2005·Journal of Assisted Reproduction and Genetics·Janos KoncSandor Cseh
Jan 12, 2007·Journal of Assisted Reproduction and Genetics·Nina JancarEda Vrtacnik Bokal
Jul 20, 2007·Journal of Assisted Reproduction and Genetics·Lars D M OttosenHans Jakob Ingerslev
Mar 3, 2012·Journal of Assisted Reproduction and Genetics·Sang Min KangSeong Goo Lee
Aug 22, 2003·Reproductive Biomedicine Online·M BungumC Yding Andersen
Dec 22, 2009·Human Reproduction·Lionel DessolleCharles Coutant
Jun 16, 2012·Journal of Biomedicine & Biotechnology·Joana ReisJosé Potes
Dec 26, 2013·BioMed Research International·Giovanna ZacchettiPatrick Ammann
Jul 9, 2013·Asian Journal of Andrology·Giuseppe Lo MonteRoberto Marci
Oct 12, 2012·Journal of Assisted Reproduction and Genetics·Daniela Paes Almeida Ferreira BragaEdson Borges
Jul 24, 2012·Journal de gynécologie, obstétrique et biologie de la reproduction·C FangX Y Liang
Jun 14, 2008·Reproductive Biomedicine Online·Monica AntinoriSeverino Antinori
Dec 10, 2002·Reproductive Biomedicine Online·Efstratios M Kolibianakis, Paul Devroey
Feb 5, 2010·Reproductive Biomedicine Online·Jun Qiang ZhangGuo Qing Tong
Dec 25, 2009·Reproductive Biomedicine Online·Daniela Paes Almeida Ferreira de BragaEdson Borges
May 5, 2009·Fertility and Sterility·Mika R ThomasBradley J Van Voorhis
Sep 18, 2004·Fertility and Sterility·James D M NicopoullosJonathan W A Ramsay
Apr 6, 2006·Fertility and Sterility·Irma Virant-KlunHelena Meden-Vrtovec
Aug 6, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Paolo Giovanni ArtiniCarla Tatone
Jan 2, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Lucie DelarocheNathalie Rougier
Mar 3, 2012·Clinical and Experimental Reproductive Medicine·Sang Min KangSeong Goo Lee
Dec 14, 2004·Human Reproduction·John C M DumoulinEdith Coonen
Aug 11, 2017·Clinical and Experimental Reproductive Medicine·Caizhu WangRuoyun Lin

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