The effect of intrapartum fetal pulse oximetry, in the presence of a nonreassuring fetal heart rate pattern, on operative delivery rates: a multicenter, randomized, controlled trial (the FOREMOST trial)

American Journal of Obstetrics and Gynecology
Christine E EastFOREMOST Study Group

Abstract

The objective of the study was to compare operative delivery rates for nonreassuring fetal status between 2 groups of laboring women: those having conventional cardiotocograph monitoring and those having cardiotocograph monitoring plus fetal pulse oximetry. The intrapartum fetal oximetry prospective, multicenter, randomized, controlled trial (the FOREMOST trial) was conducted in 4 Australian maternity hospitals. The primary outcome was operative birth rates for nonreassuring fetal status. There was a statistically significant 23% relative risk reduction in operative delivery for nonreassuring fetal status in the fetal pulse oximetry + cardiotocograph group (n = 75 of 305, 25%), compared with those in the cardiotocograph-only group (n = 95/295, 32%) (relative risk 0.77, 95% confidence interval 0.599, 0.999, P = .048). There were no significant between-group differences in overall operative births (fetal pulse oximetry + cardiotocograph group 73%, cardiotocograph-only group 71%, relative risk 1.04, 95% confidence interval 0.94, 1.15, P = .478) or neonatal outcomes. The use of fetal pulse oximetry to augment fetal well-being assessment during labor resulted in a statistically significant reduction in the operative intervention for...Continue Reading

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Citations

Aug 14, 2009·Journal of Perinatal Medicine·Philip J Steer
Dec 4, 2009·Journal of Perinatal Medicine·Andreas NonnenmacherJoachim Dudenhausen
Jan 15, 2008·Journal de gynécologie, obstétrique et biologie de la reproduction·B LangerE David
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May 18, 2006·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Christine E EastPaul B Colditz
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