The effect of intravenous nutrition on muscle mass and exercise capacity in perioperative patients

American Journal of Surgery
C D WoodM Pollard

Abstract

This study was undertaken to compare the efficacy of four different types of perioperative intravenous nutritional support. Fifty-five patients undergoing routine major surgery were studied. They were prospectively assigned to one of four study groups. Group 1 received formal total parenteral nutrition (90 g amino acids, 3,000 calories as glucose, per day); Group 2, 100 g glucose per day; Group 3, 90 g amino acids per day; and Group 4, peripheral parenteral nutrition (90 g amino acids plus 1,600 calories, 60 percent as fat per day). Group 1 was maintained on therapy for 3 weeks and the other groups for 8 days. Nitrogen balance, maintenance of body cell mass, serum albumin levels, and maintenance of exercise capacity were measured. Patients receiving peripheral parenteral nutrition maintained their nutritional parameters, as did those receiving total parenteral nutrition. These infusions were both markedly superior to those receiving glucose alone or those receiving amino acids alone. Nitrogen balance was not correlated with maintenance of function, but maintenance of body cell mass was correlated with maintenance of exercise capacity (r = 0.66, p less than or equal to 0.01). We conclude that perioperative peripheral parenteral ...Continue Reading

References

May 1, 1979·JPEN. Journal of Parenteral and Enteral Nutrition·M H SeltzerH S Fletcher
May 1, 1973·Annals of Surgery·G L BlackburnT E Hensle
Oct 1, 1984·Diseases of the Colon and Rectum·C W GuessC D Wood
Jan 1, 1983·American Journal of Surgery·H I KarlbergJ E Fischer
Jan 1, 1982·Annals of Surgery·K Y LiawJ M Kinney

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Citations

May 20, 2017·The Cochrane Database of Systematic Reviews·Joshua FeinbergJanus C Jakobsen

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