The Effect of Korean Red Ginseng on Sexual Function in Premenopausal Women: Placebo-Controlled, Double-Blind, Crossover Clinical Trial

Evidence-based Complementary and Alternative Medicine : ECAM
Ho Seok ChungKwangsung Park

Abstract

This study investigated whether Korean red ginseng (KRG) extracts could improve sexual function in premenopausal women. Forty-one premenopausal women participated in this placebo-controlled, double-blind, and crossover clinical study with administration of either three ginseng capsules (1 g per capsule) or placebo daily. After 8 weeks of medication of KRG or placebo, medication was changed for the subjects to placebo or KRG after 2 weeks of washout period. The efficacy of KRG extracts was measured by using Female Sexual Function Index (FSFI). Results. Twenty-three women completed the study. Total FSFI scores increased after KRG treatment (from 20.13 ± 2.87 to 23.98 ± 4.10, p = 0.015) and placebo treatment (from 20.06 ± 2.64 to 23.78 ± 3.28, p = 0.003). However, this change was not significantly different between the two groups (p = 0.702). KRG treatment significantly improved sexual desire, arousal, orgasm, and satisfaction domains; however, there was no treatment effect compared with placebo. There was a case of gastric discomfort after taking KRG extracts. Oral administration of KRG extracts improved sexual function in premenopausal women; however, there were no statistical significant changes compared to placebo. It implies ...Continue Reading

References

Feb 18, 1999·JAMA : the Journal of the American Medical Association·E O LaumannR C Rosen
Apr 16, 1999·European Journal of Pharmacology·E TachikawaE Takahashi
Jul 20, 2002·International Journal of Antimicrobial Agents·G M TedajoJacky Fourniat
Apr 12, 2006·Menopause : the Journal of the North American Menopause Society·Sandra R LeiblumRaymond C Rosen
Aug 30, 2008·British Journal of Clinical Pharmacology·Dai-Ja JangEdzard Ernst
Jul 25, 2009·The Journal of Sexual Medicine·Azita GoshtasebiAbbas Rahimi Foroshani
Oct 10, 2009·International Journal of STD & AIDS·K Wylie, F Malik
Dec 18, 2010·Korean journal of urology·Young-Ho KimJae-Sung Lim
Dec 24, 2010·The Journal of Sexual Medicine·Birgitte Schütt ChristensenMorten Frisch
Nov 2, 2011·International Journal of Food Sciences and Nutrition·Shun-Wan Chan
Oct 6, 2012·The Journal of Sexual Medicine·Andrea Bradford
Oct 16, 2012·Clinical Oncology : a Journal of the Royal College of Radiologists·N Thorp
Dec 13, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Hyunghee LeeMichung Yoon
Feb 15, 2013·The Journal of Sexual Medicine·Luca Incrocci, Pernille Tine Jensen
Apr 23, 2013·Hormones and Behavior·James R Roney, Zachary L Simmons
May 30, 2013·Journal of Ginseng Research·Joo Hyun JungSeon Tae Kim

❮ Previous
Next ❯

Methods Mentioned

BETA
hysterectomy
pregnancy test

Software Mentioned

Statistical Package for Social Science PC +

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.