The effect of latanoprost, bimatoprost, and travoprost on intraocular pressure after cataract surgery

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
Mustafa Kemal AriciAysen Topalkara

Abstract

The aim of this study was to evaluate the effect of preoperative topical latanoprost, bimatoprost, and travoprost administration on postoperative intraocular pressure (IOP) after phacoemulsification and posterior chamber intraocular lens (PC IOL) implantation. This prospective, randomized, double-masked study included 120 eyes of 120 consecutive, normotensive, uncomplicated cataract patients having phacoemulsification surgery with PC IOL implantation. They were randomized into 1 of 4 treatment groups, each of which had 30 patients. Two (2) h before the surgery, the patients received 0.005% latanoprost (Group 1), 0.004% bimatoprost (Group 2), 0.03% travoprost (Group 3), or placebo (Group 4, artificial tears). IOP was measured at preoperative, 4, 8, and 24 h postoperative with a Goldmann applanation tonometer. The anterior chamber was examined postoperatively 24 h for levels of cell and flare using slit-lamp biomicroscopy. The preoperative mean IOP was not statistically significant different among the four groups. In Groups 1 and 3, the mean IOP at 4, 8 and 24 h were significantly lower than the control (Group 4; P < 0.05). However, in Group 2, there was no significant difference in IOP during the study period, compared to the co...Continue Reading

References

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Citations

Dec 26, 2015·Journal of Cataract and Refractive Surgery·Yotam WeinerAsher Weiner
Nov 21, 2008·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Mustafa Unal, Iclal Yücel
Dec 18, 2019·The Cochrane Database of Systematic Reviews·Laura E DownieEsen K Akpek

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